Symmetrical Peripheral Gangrene: A Rare Complication of Malaria

  • Naresh Kumar Professor of Medicine & Head of Pulmonary Medicine, Maulana Azad Medical College, New Delhi, India. https://orcid.org/0000-0003-4581-609X
  • Niraj Bohania Senior Resident, Department of Medicine, Maulana Azad Medical College, New Delhi, India.
  • S Anuradha Director Professor, Department of Medicine, Maulana Azad Medical College, New Delhi, India.
Keywords: Malaria, Fever, SPG

Abstract

Symmetrical Peripheral Gangrene (SPG) is one of the very rare and devastating complication of malaria. We report a 45-year-old gentleman who presented with fever and blackish discoloration of digits. Examination revealed mild splenomegaly, cold peripheries with dry gangrene involving bilateral fingers and toes. Investigations revealed thrombocytopenia and transaminitis. Rapid malaria test was positive for both Plasmodium falciparum and Plasmodium vivax. Patient was treated with antimalarials. Clinicians managing malaria should be more vigilant for this rare devastating complication.

How to cite this article:
Kumar N, Bohania N, Anuradha S. Symmetrical Peripheral Gangrene: A Rare Complication of Malaria. J Adv Res Med 2019; 6(3): 16-18.

DOI: https://doi.org/10.24321/2349.7181.201915

References

Sharma BD, Kabra SR, Gupta B. Symmetrical peripheral gangrene. Trop Doct 2004; 34(1): 2-4.

Available from: https://journals.sagepub.com/doi/abs/10.1177/004947550403400102 [PubMed/ Google

Scholar].

Nicholas JW, Joel GB. Malaria. In: Longo DL, Fauci AS, Kasper DL, et al, editors. Harrison’s Principles of

Internal Medicine. 18th ed. McGraw Hill, New York. 2012; 1688-703.

Clemens R, Pramoolsinsap C, Lorenz R, Pukrittayakamee S, Bock HL, White NJ. Activation of the coagulation

cascade in severe falciparum malaria through the intrinsic pathway. Br J Haematol 1994; 87(1): 100-105.

Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2141.1994.tb04877.x?sid=nlm%3A

pubmed [PubMed/ Google Scholar].

Philips RE, Looaresuwan S, Warrell DA, Lee SH, Karbwang J, Warrell MJ et al. The importance of

anaemia in cerebral and uncomplicated falciparum malaria: role of complications, dyserythropoesis, and

iron sequestration. Quart J Med 1986; 58(227): 305-323. Available from: https://academic.oup.com/qjmed/

article-abstract/58/3-4/305/1560540?redirectedFrom=PDF [PubMed/ Google Scholar].

Ghosh SK, Bandyopadhyay D. Symmetrical peripheral gangrene. Indian J Dermatol Venerol Leprol 2011; 77(2):

-248. Available from: http://www.ijdvl.com/article.asp?issn=0378-6323;year=2011;volume=77;issue=2;s

page=244;epage=248;aulast=Ghosh [Google Scholar].

Parmar MS. Symmetrical peripheral gangrene: a rare but dreadful complication of sepsis. CMAJ 2002; 167(9):

-1038. Available from: https://www.cmaj.ca/content/167/9/1037.long [PubMed/ Google Scholar].

Ghosh S, Bandyopadhyay D, Ghosh A. Symmetrical peripheral gangrene: a prospective study of 14

consecutive cases in a tertiary-care hospital in eastern India. Journal of the European Academy of Dermatology

and Venereology 2010; 24: 214-218. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/

j.1468-3083.2009.03329.x [PubMed/ Google Scholar].

Kumbhalkar S, Aher S, Wanjari S. Symmetrical peripheral gangrene: A rare complication of Plasmodium

falciparum malaria. Ann Trop Med Public Health 2017; 10(1): 238-240. Available from: http://www.atmph.

org/article.asp?issn=1755-6783;year=2017;volume=10;issue=1;spage=238;epage=240;aulast=Kumbhalkar.

Prabhat K, Ghazal T, Gupta H, Dixit J. Symmetrical peripheral gangrene in severe Plasmodium Vivax

malaria. Indian J Crit Care Med 2017; 21: 245-246. Available from: https://www.ijccm.org/doi/

pdf/10.4103/ijccm.IJCCM_424_16 [PubMed/ Google Scholar].

Published
2020-02-25