A Case Report of Severe Hypokalemic Quadriparesis as the First Manifestation of Type 1 RTA in Primary Sjogrenâ€™s Syndrome

Ramesh Aggarwal; S Sidharth; Ankit Gupta; Meenakshi Aggarwal; Ashish Kumar Singh

Ramesh Aggarwal Professor, Department of Medicine, Lady Hardinge Medical College, New Delhi, India.
S Sidharth Postgraduate Resident, Department of Medicine, Lady Hardinge Medical College, New Delhi, India. https://orcid.org/0000-0003-0455-9349
Ankit Gupta Assistant Professor, Department of Medicine, Lady Hardinge Medical College, New Delhi, India.
Meenakshi Aggarwal Specialist & Incharge, Microbiology Laboratory, Kalawati Saran Children Hospitals, LHMC, New Delhi, India.
Ashish Kumar Singh Senior Resident, Department of Medicine, Lady Hardinge Medical College, New Delhi, India.

Keywords: Primary Sjogrenâ€™s Syndrome, Type 1 Renal Tubular Acidosis, Periodic Quadriparesis, Hypokalemia

Abstract

Primary Sjogrenâ€™s syndrome is an autoimmune disorder primarily involving the exocrine glands but it can have a varied presentation. It can also present without classically described sicca symptoms. Onethird of the patients experience extra-glandular involvement in the form of nonspecific arthralgia, myalgia, arthritis, parenchymal involvement of renal parenchyma, lung, and rarely nerves. Renal involvement in primary Sjogrenâ€™s can present with type 1 renal tubular acidosis (RTA) and is associated with a normal anion gap and hypokalemia. We, hereby, report a case of primary Sjogrenâ€™s syndrome presenting with type 1 RTA with hypokalemic quadriparesis as the first presenting feature.

How to cite this article:
Aggarwal R, Sidharth S, Gupta A, Aggarwal M, Singh AK. A Case Report of Severe Hypokalemic Quadriparesis as the First Manifestation of Type 1 RTA in Primary Sjogrenâ€™s Syndrome. J Adv Res Med. 2021;8(2):27-29.

DOI: https://doi.org/10.24321/2349.7181.202111

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