Mucin2 and Lipid Profile Estimation in Giardia Lamblia Infected Patients: A Case-control Study
Introduction: Globally, Giardia duodenalis (G. lamblia) is a protozoan parasite that has the ability to cause sporadic or epidemic infectious diarrhoea. Giardia infection is a crucial cause of waterborne and foodborne disease, outbreaks in the daycare centre, and international travel-related infection. This study aimed to evaluate the effects of Giardia lamblia infection on serum MUC2 and lipid profile.
Patients and Methods: From March to April 2021, a case-control study was conducted on 48 patients with giardiasis who attended AL-Hakeem Hospital in Najaf Province in Iraq and 24 healthy adults as a control group. Stool examinations were done using standard techniques for the identification of the parasitic infection.
Results: The results showed a significantly higher concentration (130.57 ± 4.04 ng/ml, and 130.11 ± 3.6 ng/ml) (p of MUC2 in G. lamblia infected patients (males and females) in comparison to the individuals of the control group. In addition, significantly higher concentrations (p < 0.05) of cholesterol, VLDL, TG, and LDL were found in comparison to the control individuals, whereas the concentration of HDL was significantly lower (p in patients infected with G. lamblia as compared to the control group.
Conclusion: The current study revealed that MUC2 and lipid profile are valuable biomarkers that help in the diagnosis of G. lamblia parasite infection.
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