IL-6-174 G/C Polymorphism in COVID-19 Pregnant Women

Iman Salman Hassan

Iman Salman Hassan PhD in Nursing, North Technical University, Technical Institute, Kirkuk, Iraq.

Keywords: IL-6 (-174) G/C, Pregnant Women, COVID-19

Abstract

Introduction: Cytokines play a role in severely ill patients with COVID-19. Similarly, there are roles of other pro-inflammatory responses in COVID-19 pathogenesis.

Objective: To detect IL-6 G/C +174 polymorphisms in COVID-19 pregnant women.

Method: 77 blood samples were collected from pregnant women with COVID-19 and 25 samples of healthy pregnant women (age range: 20-35 years). The blood samples of pregnant women with COVID-19 were collected (from the 1st of August to the 25th of December, 2020) from Azasi Teaching Hospital and Al-Jumhuri Hospital in Kirkuk, Iraq.

Results: The results showed that C allele in pregnant women with COVID-19 was 31(40.3%) compared to with allele G, which is 46(59.7%), while the allele C was 19(76%), compared to the allele A, which is 6(34%) in healthy pregnant women.

Conclusion: G allele demonstrates significant frequency in pregnant women with COVID-19 and higher rate compared with healthy pregnant women, and G allele may represent a significant risk factor for COVID-19 in the Iraqi population and there is an association between IL-6-174 G/C polymorphism and COVID-19 patients.

How to cite this article:
Hassan IS. IL-6-174 G/C Polymorphism in COVID-19 Pregnant Women. Special Issue - COVID-19 & Other Communicable Disease. 2022;177-180.

DOI: https://doi.org/10.24321/0019.5138.202228

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