Association between Chronic Obstructive Pulmonary Disease and Severity of COVID-19 in a Tertiary Care Centre of Pune City, Maharashtra
Association of COPD and COVID-19 severity
Abstract
Background: COVID-19 is a global pandemic caused by SARS-CoV2, spreading across every continent in world. The risk of developing severe COVID-19 with underlying disorder like COPD might be higher as compared to patients with no comorbidity. This study was undertaken to assess the association between COPD and severity of COVID-19.
Material & Methods: This was a hospital-based cohort study conducted between July to December, 2020. Study subjects were confirmed COVID-19 patients admitted to this tertiary care centre and all patients were followed up to final outcome as discharge or death. Depending upon the history of COPD total 113 COVID-19 patients with COPD (exposed) and 339 COVID-19 patients without history of COPD (unexposed) were included in analysis. Statistical analysis was done using logistic regression analysis, and adjusted odd’s ratio with 95% CI were calculated.
Results: Age >60 years (OR = 1.38, 95% CI 1.12–3.30) and breathlessness (OR = 2.42, 95% CI 1.21–4.85) were independent risk factors for mortality in COVID-19 patients. In addition to this, other co-morbidities were associated with mechanical ventilation. On multivariable analyses, COPD was not significantly associated with mortality in COVID-19 (OR 0.93; 95% CI 0.15–1.58).
Conclusion: Underlying COPD was not an independent risk factor for poor outcome in COVID-19 patients.
How to cite this article:
Hatnapure M, Parande MA, Tambe MP, Jagdale GR, Salunke P, Mule N, Pawar V. Association between Chronic Obstructive Pulmonary Disease and Severity of COVID-19 in a Tertiary Care Centre of Pune City, Maharashtra. Special Issue - COVID-19 & Other Communicable Disease. 2022;24-29.
DOI: https://doi.org/10.24321/0019.5138.202204
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