A Rare Encounter of Syndrome of Inappropriate Antidiuretic Hormone Secretion in Localised Herpes Zoster (Shingles)

Rehab Yasir  Nainar; Kaliyannan Mayilananthi; Durga Krishnan; Thuvaragah; Rajat Pande

Rehab Yasir Nainar Postgraduate Resident, Department of General Medicine, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam, Kancheepuram, Tamil Nadu, India.
Kaliyannan Mayilananthi Professor, Department of General Medicine, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam, Kancheepuram, Tamil Nadu, India.
Durga Krishnan Professor, Department of General Medicine, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam, Kancheepuram, Tamil Nadu, India.
Thuvaragah Senior Resident, Department of General Medicine, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam, Kancheepuram, Tamil Nadu, India.
Rajat Pande Postgraduate Resident, Department of General Medicine, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam, Kancheepuram, Tamil Nadu, India.

Keywords: SIADH, Hyponatremia, Herpes Zoster

Abstract

Background: There have been many case reports previously stating Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) as a manifestation of disseminated herpes zoster virus infection.
Objective: The case report adds light to localised herpes zoster as a rare cause of SIADH, an often-under-diagnosed entity.
Methodology: We report a 70-year-old female who was found in a state of altered sensorium after a presentation of itching and skin lesions over the left thoracic T (T7) region.
Results: Laboratory investigations revealed euvolemic hyponatremia and the patient was diagnosed to have SIADH. Treatment was given for the aetiology of SIADH and to treat the euvolemic hyponatremia.
Conclusion: Treatment of SIADH caused by localised herpes zoster shows quick recovery with the resolution of the herpetic lesions.

How to cite this article:
Nainar RY, Mayilananthi K, Krishnan D, Thuvaragah, Pande R. A Rare Encounter of Syndrome of Inappropriate Antidiuretic Hormone Secretion in Localised Herpes Zoster (Shingles). J Commun Dis. 2022;54(1):22-24.

DOI: https://doi.org/10.24321/0019.5138.202244

References

Sahay M, Sahay R. Hyponatremia: a practical approach. Indian J Endocrinol Metab. 2014 Nov;18(6):760-71. [PubMed] [Google Scholar]

Yasir M, Mechanic OJ. Syndrome of inappropriate antidiuretic hormone secretion. Treasure Island (FL): Stat Pearls Publishing; 2021 Jan. [Google Scholar]

Mentrasti G, Scortichini L, Berardi R. Syndrome of inappropriate antidiuretic hormone secretion (SIADH): optimal management. Ther Clin Risk Manag. 2020 Jul;16:663-72. [PubMed] [Google Scholar]

Semel JD, McNerney JJ Jr. SIADH during disseminated herpes varicella-zoster infections: relationship to vidarabine therapy. Am J Med Sci. 1986 Feb;291(2):115-8. [PubMed] [Google Scholar]

Gnann Jr JW. Varicella-zoster virus: atypical presentations and unusual complications. J Infect Dis. 2002 Oct;186 Suppl 1:S91-8. [PubMed] [Google Scholar]

Bassi V, Fattoruso O, Santinelli C. Localized herpes zoster infection: a rare cause of syndrome of inappropriate secretion of antidiuretic hormone. Oxf Med Case Reports. 2017 Nov;2017(11):omx065. [PubMed] [Google Scholar]

Wang CC, Shiang JC, Chen JT, Lin SH. Syndrome of inappropriate secretion of antidiuretic hormone associated with localized herpes zoster ophthalmicus. Gen Intern Med. 2010 Feb;26:216-20. [PubMed] [Google Scholar]

Azimi SZ, Firooz A. Postherpetic abdominal pseudohernia: an uncommon complication of herpes zoster. Dermatologic Ther. 2020 Jul;33(4):e13530. [PubMed] [Google Scholar]

Teo HK, Chawla M, Kaushik M. A rare complication of herpes zoster: segmental zoster paresis. Case Rep Med. 2016;2016:7827140. [PubMed] [Google Scholar]

Gross P. Clinical management of SIADH. Ther Adv Endocrinol Metab. 2012 Apr;3(2):61-73. [PubMed] [Google Scholar]