Antimicrobial Susceptibility Pattern of Isolates of Streptococcus pyogenes obtained from Patients with Throat Infection

Abstract

Background: Streptococcus Group A (GAS) or Streptococcus pyogenes are major causes of infectious diseases, including upper respiratory tract illnesses, especially throat infections. This infection involves the inflammation of pharyngitis. Recently, streptococcal species have shown a wide range of antimicrobial resistance.

Method: Sixty-four throat specimens were collected using a sterile broth tube and transferred to the bacteriological laboratory unit. These specimens were grown on different media and were then primarily
identified using several types of biochemical tests and the process was completed through the VITEK 2 system for diagnosis of Streptococcus pyogenes and Streptococcus spp. The antibiotic susceptibility pattern of these bacterial isolates was identified on the Muller-Hinton Agar.
Results: The percentage of positive bacterial growth was equal to 55. The Streptococcus pyogenes growth was detected in 17.14% of the sample (66.67% in males and 33.33% in females). The antimicrobials levofloxacin, azithromycin, amikacin, norfloxacin, trimethoprim, erythromycin, and amoxicillin are effective against various samples of Streptococcus pyogenes with an efficacy of 66.67%.
Conclusion: Streptococcus pyogenes (GAS) is one of the major causes of throat infection. These infections are more common in males than females. The antimicrobials levofloxacin, azithromycin, amikacin, norfloxacin, trimethoprim, erythromycin, and amoxicillin are effective against Streptococcus pyogenes.

How to cite this article:
Hussein E F, Raheem H Q, Merdas A H.
Antimicrobial Susceptibility Pattern of Isolates
of Streptococcus pyogenes obtained from
Patients with Throat Infection. J Commun Dis.
2024;56(3):17-21.

DOI: https://doi.org/10.24321/0019.5138.202444