Persistent symptoms at the end of 3 months after Acute COVID-19 infection among adult patients admitted to a tertiary care centre: A descriptive longitudinal study

Priyanka  H Salunke; Varsharani  V Kendre; Malangori  A Parande; Ashwini  U Patekar; Muralidhar  P Tambe; Yallapa UJadhav; Ganesh  R Jagdale; Minal  Hatnapure; Pradip  Borle; Pradnya  V Shinde; Namrata  D Mule; Rupali N  Baviskar; Shubham  S Pardeshi

Priyanka H Salunke Senior Resident, Department of Community Medicine, B J Government Medical College, Pune, India.
Varsharani V Kendre Associate Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Malangori A Parande Associate Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Ashwini U Patekar Assistant Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Muralidhar P Tambe Professor and Head, Department of Community Medicine, B J Government Medical College, Pune, India.
Yallapa UJadhav Associate Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Ganesh R Jagdale Medical Officer, Pune Municipal Corporation, Pune, India.
Minal Hatnapure Junior Resident, Department of Community Medicine, B J Government Medical College, Pune, India.
Pradip Borle Statistician cum Assistant Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Pradnya V Shinde Assistant Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Namrata D Mule Assistant Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Rupali N Baviskar Assistant Professor, Department of Community Medicine, B J Government Medical College, Pune, India.
Shubham S Pardeshi Junior Resident, Department of Community Medicine, B J Government Medical College, Pune, India.

Keywords: Acute Covid-19, Persistent symptoms, longitudinal study, Post-COVID-19

Abstract

Background: COVID-19 has affected all corners of the world. Multiple symptoms reported during the hospital stay may persist after the patient discharged from the hospital. Objectives: 1) To study the persistence of symptoms at the end of 3 months after acute COVID-19 infection among adult patients admitted to a tertiary care centre. 2) To review their symptoms during the acute COVID-19 infection. 3) To study the association between various factors and the persistence of symptoms of acute COVID-19 infection.
Material & Method: This was a descriptive longitudinal study conducted in November 2021. The sample included 200 laboratory-confirmed COVID-19 cases discharged from the tertiary care hospital of Pune City after obtaining written informed consent.Epidemiological information was obtained by telephonic interview with predesigned and pretested proforma covering socio-demographic data, related factors and information about the onset and duration of symptoms after the patient was discharged from the hospital.
Results: The study involved 200 recovered COVID-19 patients (115 males, 85 females) with a mean age of 46.42 ± 16.22 years. Notably, 90% of males had some form of addiction, compared to 10% of females, revealing a significant gender disparity (p value <0.0001). Fatigue (75.50%), cough (73%), and fever > 38.0 OC(69.50%) were prevalent persistent symptoms. A statistically significant association of persistence of symptoms was found with age and COVID-19 vaccination status.
Conclusion: Our study provides crucial insights into long-term COVID-19 symptoms, advocating targeted interventions considering demographic factors. This comprehensive approach guides effective management of persistent symptoms post-COVID-19.

Salunke P H, Kendre V V, Parande M A, Patekar A
U, Tambe M P, Jadhav Y U, Jagdale G R, Hatnapure
M, Borle P, Shinde P V, Mule N D, Baviskar R N,
Pardeshi S S. Persistent Symptoms at the End of
3 Months after Acute COVID-19 Infection among
Adult Patients Admitted to a Tertiary Care Centre:
A Descriptive Longitudinal Study. J Commun Dis.
2024;56(3):119-126.

DOI: https://doi.org/10.24321/0019.5138.202456

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