Biofilm Formation of Staphylococcus saprophyticus  Urinary Tract Infection and Cytokine Response  in Reproductive Age Women

Samira  Ayoob Hameed; Rafal  Khaleel Farhan

Samira Ayoob Hameed Department of medical microbiology, Tikrit University, Salaheddin, Iraq.
Rafal Khaleel Farhan Department of medical microbiology, Tikrit University, Salaheddin, Iraq.

Keywords: UTI, Staphylococcus saprophyticus, Biofilm formation, cytokine

Abstract

Introduction: A cross-sectional study was conducted during the period extending from the first of November 2022 to the end of Jun 2023. In this study, 425 women aged between 15-45 years old were selected.
Material and methods: Urine samples were cultured and IL17 and CXCL1 levels were determined by using the enzyme-linked Immunosorbent assay (ELISA) technique.
Results: The urine culture revealed that 65.65% of urine samples were positive for bacteria while 34.35% were negative. The study showed that urinary tract infection Staphylococcus saprophyticus is most common
in the age group of 15-25 years old (45.2%) and in the age group 26-35 years old it was 38.1% while the lowest rate was within the age group of 36-45 years old (16.7%). Biofilm formation was 92.9%. The current study shows that the mean urine IL-17 level among the study group had non-significant differences compared with that of the control group.
Conclusion: The study shows that urine CXCL1 mean level of reproductive age women with UTI where statistically significant as compared to the control group.

How to cite this article:
Hameed S A, Farhan R K. Biofilm Formation
of Staphylococcus saprophyticus Urinary Tract
Infection and Cytokine Response in Reproductive
Age Women. J Commun Dis. 2024;56(3):22-30.

DOI: https://doi.org/10.24321/0019.5138.202445

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