Effect of Vitamin D Supplementation on Serum Cytokines Expression in Lymphatic Filariasis Patients with Type 2 Diabetes Mellitus: A Pilot Study

  • Awanindra Dwivedi National Centre for Disease Control, DGHS, MoH&FW, GOI, Varanasi, Uttar Pradesh, India.
  • Vetrivel Baskar National Centre for Disease Control, DGHS, MoH&FW, GOI, Varanasi, Uttar Pradesh, India.
  • Awadhesh Kumar Yadav National Centre for Disease Control, DGHS, MoH&FW, GOI, Delhi, India.
  • Subha Garg National Centre for Disease Control, DGHS, MoH&FW, GOI, Delhi, India.
  • Vinay Kumar Garg National Centre for Disease Control, DGHS, MoH&FW, GOI, Delhi, India.
  • Ravi Ranjan All India Institute of Medical Sciences, New Delhi, India.
  • Atul Goel National Centre for Disease Control, DGHS, MoH&FW, GOI, Delhi, India.

Abstract

Introduction: Introduction: More than 100 million population worldwide are infected with one of the three lymph-dwelling filariae (Wuchereria bancrofti, Brugia malayi or B. timori), the major causative agents of lymphatic filariasis (LF). The disease burden from LF is concentrated in tropical and sub-tropical countries (such as India) where the prevalence of type 2 diabetes (T2DM) is the greatest. Uncontrolled T2DM manifests as chronic low-grade inflammation and leads to alteration of the functioning of the innate immune system. Active vitamin D hormone promotes innate immune response in antigen-presenting cells.

How to cite this article:
Dwivedi A, Baskar V, Yadav AK, Garg S, Garg VK, Ranjan R, Goel A. Effect of Vitamin D Supplementation on Serum Cytokines Expression in Lymphatic Filariasis Patients with Type 2 Diabetes Mellitus: A Pilot Study. XIV Annual Conference of Indian Society for Malaria & Other Communicable Diseases (ISMOCD). 2023;25-29.

DOI: https://doi.org/10.24321/0019.5138.202332

References

World Health Organization [Internet]. Lymphatic filariasis; 2023 Jun 1 [cited 2023 Jul 25]. Available from: https://www.who.int/news-room/fact-sheets/detail/lymphatic-filariasis

World Health Organization [Internet]. Diabetes; 2023 Apr 5 [cited 2023 Jul 18]. Available from: https://www.who.int/news-room/fact-sheets/detail/diabetes

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Published
2023-10-21