https://medical.advancedresearchpublications.com/ojs-3.1.2-4/index.php/MedicineJournal/issue/feed 2026-04-23T04:42:57+00:00 Advanced Research Publications admin@adrpublications.in Open Journal Systems https://medical.advancedresearchpublications.com/ojs-3.1.2-4/index.php/MedicineJournal/article/view/5109 2026-04-23T04:42:57+00:00 Naresh Kumar drnareshmamc@gmail.com Princy Poonam drnareshmamc@gmail.com Shipra Anand drnareshmamc@gmail.com Amitesh Gupta drnareshmamc@gmail.com Harpreet Singh drnareshmamc@gmail.com Sandeep Garg drnareshmamc@gmail.com Gaurav Shankar Pradhan drnareshmamc@gmail.com Rashmi Mishra drnareshmamc@gmail.com

<p>Background: Persistent pulmonary dysfunction after COVID-19 pneumonia recovery remains a concern, with restrictive patterns commonly reported. This study assessed spirometric abnormalities in patients recovered from COVID-19 pneumonia and their associations with comorbidities, smoking, and disease severity.<br>Methods: A prospective cohort study enrolled 53 adults (&gt;18 years) discharged from COVID-19 wards after 6–12 weeks post-diagnosis. Inclusion required RT-PCR/RAT confirmation and bilateral infiltrates on chest imaging; exclusions included pre-existing respiratory/cardiac disease, obesity (BMI &gt;30 kg/m²), and pregnancy. Spirometry (Schiller Spirovit SP1) was performed at 6–12 weeks and repeated 3 months later. Data was analyzed using SPSS v25, with chi-square, t-tests, ANOVA, and logistic regression (p &lt; 0.05 is significant).<br>Results: The mean age of the subjects was 54.5 ± 12.3 years; 83% were male, 75% with comorbidities (mostly diabetes/hypertension), and 94% nonsmokers. Clinical severity: 49% of subjects had mild, 26% of subjects had moderate, and 25% of subjects had severe disease clinically and had a mean CTSS of 12.25 ± 5.96. Abnormal spirometry was found in 28.3% of subjects at the first follow-up (mostly restrictive, 20.8%) and 17% at the second follow-up (13.2% restrictive). Improvement noted in pulmonary function was statistically not insignificant (p = 0.441). Nonsmokers had better outcomes (p = 0.043 first and p = 0.001 second); severe cases showed more defects.<br>Conclusion: Restrictive ventilatory defect predominates post-COVID-19, with improvement over 3 months, influenced by smoking and severity. Larger studies including DLCO/plethysmography are needed.</p> <p><strong>DOI:</strong>10.24321/2349.7181.202507</p> <p><strong>How to cite this article:</strong><br>Poonam P, Anand S, Gupta A, Singh H, Garg S, Pradhan G S, Mishra R, Kumar N. Breath After the Storm: Longitudinal Spirometry in COVID 19 Survivors- A prospective cohort study. J Adv Res Med 2025; 12(3): 1-8.</p>

2026-04-21T00:00:00+00:00 Copyright (c) 2026 Naresh Kumar, Princy Poonam, Shipra Anand, Amitesh Gupta, Harpreet Singh, Sandeep Garg, Gaurav Shankar Pradhan, Rashmi Mishra