Occurrence of Thyroid Dysfunction and Associated Metabolic Abnormalities among Adults Attending a Tertiary Care Hospital in Kathmandu

Suman  Pradhan; Anisha Koirala; Ritesh Shrestha

Suman Pradhan Assistant Professor, Department of Internal Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
Anisha Koirala Associate Professor, Department of Internal Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
Ritesh Shrestha Lecturer, Department of Internal Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Keywords: Endocrine disorders, Thyroid dysfunction, Hypothyroidism, Metabolic abnormalities

Abstract

Background

Endocrine disorders, particularly thyroid dysfunction, are increasingly prevalent worldwide and significantly contribute to metabolic disturbances and reduced quality of life. Early diagnosis and management are essential for preventing complications.

Objective

To assess the prevalence of thyroid dysfunction and associated metabolic abnormalities among adults attending a tertiary care hospital in Nepal.

Methods

A hospital-based cross-sectional study was conducted among 240 adults attending endocrine and general medicine outpatient departments. Thyroid function tests, fasting blood glucose, lipid profile, body mass index, and blood pressure were evaluated.

Results

Hypothyroidism was identified in 28.3% participants, while hyperthyroidism was observed in 11.7%. Thyroid dysfunction was significantly associated with obesity, dyslipidemia, hypertension, and impaired fasting glucose (p<0.05). Female participants demonstrated higher prevalence of thyroid abnormalities compared to males.

Conclusion

Thyroid dysfunction is highly prevalent among adults in Nepal and is significantly associated with metabolic abnormalities. Routine endocrine screening and lifestyle modification strategies are essential for early diagnosis and prevention of complications.

DOI: https://doi.org/10.24321/2349.2880.202615

How to cite this article:
Pradhan S, Koirala A, Shrestha R. Occurrence of Thyroid Dysfunction and Associated Metabolic Abnormalities Among Adults Attending a Tertiary Care Hospital in Kathmandu. J Adv Res Med 2026; 13(2): 1-8.

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