Transient Neonatal Hyperinsulinemia: Timely Diagnosis and Treatment
Abstract
Hyperinsulinism (HI) is the leading cause of persistent hypoglycaemia in newborns. Diazoxide inhibits the secretion of insulin and is the first-line drug for controlling hypoglycaemia secondary to prolonged transient hyperinsulinemia or permanent hyperinsulinemia, thus it prevents hypoglycaemia and the permanent neurological sequelae associated with hypoglycaemia. We report two neonates who presented with hypoglycaemia which was refractory. Investigations revealed hyperinsulinism and both neonates responded to treatment with oral diazoxide. Timely screening and prompt treatment of hypoglycaemia are recommended as it is linked to poor neuro developmental outcomes in the long term.
How to cite this article:
Megha P, Ashwini RC. Transient Neonatal Hyperinsulinemia: Timely Diagnosis and Treatment. Postgrad J Pediatr Adol Med. 2022;1(1):59-61.
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