Clinico-epidemiological Profile and Social Stigma in Hospitalised RT-PCR Confirmed COVID-19 Cases with and without Comorbidity
Abstract
Introduction: The unprecedented COVID-19 outbreak has now spread to every nook of the world. It has contributed to an enormous adverse impact globally. Persons of every age group are likely to get infected but elderly people or those with comorbidities could develop a more serious illness.
Objectives: To describe the clinico-demographic characteristics, various risk factors, and COVID-19 related social stigma among 135 hospitalised patients in north India and to find an association by comparing it with comorbidity.
Methods: The present study is an observational analytical study carried out on 135 patients with RT-PCR confirmed cases admitted in a tertiary care hospital India aged between 15-79 years. Data were collected in a validated questionnaire specially designed for COVID-19 by National Centre for Disease Control (NCDC).
Result: A total of 135 patients were included (median age, 40 years [interquartile range {IQR}, 54-29; range, 15-79 years]; 62.9% Male). The presenting symptoms at the time of admission were fever (57.0%), cough (43.0%), fatigue (42.2%), and breathlessness (28.1%). The most prevalent comorbidities were hypertension (20%), diabetes (14.1%), thyroid disorder (6.7%), cardiovascular diseases (3.7%), and chronic obstructive pulmonary disease (4.4%) and 23.7% patients reported having at least one comorbidity. Patients without pre-existing diseases have more social stigma as compared to patients with comorbidities. Twenty eight percent reported use of AYUSH therapies as prophylactic measures.
Conclusion: This study describes the clinico-demographic profile, baseline comorbidities, and social stigma associated with COVID-19 patients. Patients having comorbidity have less stigma, however, the family of both the groups were worried and supportive.
How to cite this article:
Nazli T, Kishore J, Raheem A, Ansari IA, Ghai AS, Heena. Clinico-epidemiological Profile and Social Stigma in Hospitalised RT-PCR Confirmed COVID-19 Cases with and without Comorbidity. Epidem Int 2021;6(1):1-8.
DOI: https://doi.org/10.24321/2455.7048.202101
References
WHO [Internet]. Coronavirus Disease (COVID-19) [cited 2020 Jan 13]. Available from: https://covid19.who.int/
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng
Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in
Wuhan, China. JAMA. 2020; 323(11):1061-9. [PubMed] [Google Scholar].
Biswas M, Rahaman S, Biswas TK, Haque Z, Ibrahim B. Association of Sex, Age, and Comorbidities with
Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Intervirology. 2021;64:36-47.
doi: https://doi.org/10.1159/000512592. [PubMed] [Google Scholar].
National Centre for Disease Control [Internet]. Form A. Available from: https://ncdc.gov.in/WriteReadData/
l892s/392888771580884195.pdf
Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, Liu XQ, Chen RC, Tang CL, Wang T, Ou CQ, Li L, Chen PY,
Sang L, Wang W, Li JF, Li CC, Ou LM, Cheng B, Xiong S, Ni ZY, Xiang J, Hu Y, Liu L, Shan H, Lei CL, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Cheng LL, Ye F, Li SY, Zheng JP, Zhang NF, Zhong NS, He JX, China Medical Treatment Expert Group for COVID-19. Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis. Eur Respir J. 2020 May 14;55(5):2000547.
doi: https://doi.org/10.1183/13993003.00547-2020.[PubMed] [Google Scholar].
Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, Northwell COVID-19 Research
Consortium. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized
With COVID-19 in the New York City Area. JAMA.2020;323(20):2052-9. doi: https://doi.org/10.1001/
jama.2020.6775. [PubMed] [Google Scholar].
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, Li H, Wu X, Xu J, Tu S,
Zhang Y, Chen H, Cao B. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in
Wuhan, China: a retrospective cohort study. Lancet.2020;395(10229):1054-62. [PubMed] [Google Scholar].
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X,
Yin W, Li H, Liu M, Xiao Y, Hong G, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B. Clinical features
of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.
[PubMed] [Google Scholar].
Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, Ji R, Wang H, Wang Y, Zhou Y. Prevalence of comorbidities
and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis.
;94:91-5. [PubMed] [Google Scholar].
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y, Xia J, Yu T, Zhang X, Zhang L.
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China:
A descriptive study. Lancet. 2020;395(10223): 507-13.[PubMed] [Google Scholar].
Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, Akdis CA, Gao YD. Clinical characteristics of 140 patients
infected with SARSâ€CoVâ€2 in Wuhan, China. Allergy. 2020;75:1730-41. [PubMed] [Google Scholar].
Gupta N, Agrawal S, Ish P, Mishra S, Gaind R, Usha G, Singh B, Sen MK, Safdarjung Hospital Covid Working
Group. Clinical and epidemiologic profile of the initial COVID-19 patients at a tertiary care centre in India.
Monaldi Arch Chest Dis. 2020;90:1294. [PubMed][Google Scholar].
Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP, Xiao W, Wang YN, Zhong MH, Li CH, Li GC, Liu HG. Clinical
characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J. 2020 May
;133(9):1025-31. [PubMed] [Google Scholar].
Mohan A, Tiwari P, Bhatnagar S, Patel A, Maurya A, Dar L, Pahuja S, Garg R, Gupta N, Sahoo B, Gupta R,
Meena VP, Vig S, Pandit A, Mittal S, Madan K, Hadda V, Dwivedi T, Choudhary A, Brijwal M, Soneja M, Guleria
R, Ratre B, Kumar B, Bhopale S, Panda S, Singh AR, Singh S, Wundavalli L. Clinico-demographic profile &
hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res.
;152(1):61-9. doi: https://doi.org/10.4103/ijmr.IJMR_1788_20. [PubMed] [Google Scholar].
Kishore J, Bharti A, Heena, Yadav G, Gupta N, MeenaR. Risk Factors of COVID-19 among Patients Attending
a Tertiary Care Centre in Delhi: A Case Control Study. Epidem Int. 2020;5(4):5-11. [Google Scholar].
Heena, Nazli T, Grover S, Kishore J. Covid-19 Pandemic and “Feeling Depressedâ€: An Online Survey. Epidem
Int. 2020;5(2):27-31. [Google Scholar].
World Health Organisation [Internet]. Social Stigma associated with COVID-19. [cited 2020 Aug 15].
Available from: https://www.who.int/docs/defaultsource/coronaviruse/covid19-stigma-guide.pdf
Kishore J, Anand T, Heena, Nazli T. Depression during COVID-19 Pandemic in India: Findings from an Online
Survey. Int J Preven Curat Comm Med 2020; 6(2): 16-21.
Nazli T, Heena, Raheem A, Kishore J. Perceptions and Practices of the Adult Population in Response to SARSCoV-2 Pandemic in India. Epidem Int. 2020;5(2):10-16. [Google Scholar].
