Chettinad Health City Medical Journal (E-2278-2044 & P-2277-8845) https://medical.advancedresearchpublications.com/index.php/CHCMJ <h3><em>Chettinad Health City Medical Journal</em> is a UGC Approved Journal.</h3> en-US admin@adrpublications.in (Admin) Mon, 30 Sep 2024 14:38:34 +0000 OJS 3.1.2.3 http://blogs.law.harvard.edu/tech/rss 60 The Burnout Epidemic: A Crisis among Healthcare Professionals https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3791 <p><strong>How to cite this article:</strong><br>Raja D. The Burnout Epidemic: A Crisis among Healthcare Professionals. Chettinad Health City Med J. 2024;13(3):1-4.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202436</p> Raja D Copyright (c) 2024 Raja D https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3791 Mon, 30 Sep 2024 09:02:39 +0000 A Pre-Experimental Study to Assess the Effectiveness of Structured Teaching Programme (STP) in Terms of Awareness of Female Students Regarding Human Papillomavirus (HPV) and its Vaccine in a Selected School of New Delhi https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2159 <p><strong>Introduction:</strong> Human Papillomavirus (HPV) infection can also cause a number of anogenital malignancies, including head and neck cancers as well as cancers of the anus, vulva, vagina, and penis. Around 70% of all instances of cervical cancers are caused by HPV types 16 and 18. Nowadays, HPV vaccinations that offer defence against HPV 16 and 18 infections may lower the occurrence of cervical and other anogenital<br>malignancies.&nbsp;<br><strong>Objective:</strong> The study aimed to assess the awareness of female students regarding HPV and its vaccine, to assess the efficacy of a Structured Teaching Programme (STP) in increasing their awareness, and to analyse the<br>association of the awareness scores with selected demographic variables.<br><strong>Method:</strong> The conceptual framework for the study was based on the CIPP model developed by Daniel Stufflebeam (1971). The study used a quantitative research strategy with a pre-experimental research design<br>with one group pretest post-test design. A standardised questionnaire was created to test female pupils’ awareness. The validity and reliability of the tool were established. Descriptive and inferential statistics were used to analyse data. Purposive sampling was used to get 130 samples.<br><strong>Results:</strong> The study’s findings revealed that the majority of the subjects were in the age group of 12-14 years, with 78 (60%) followed by 52 (40%) in the age group of 15-17 years, and the data showed that there<br>was a gain in the post-test modified mean percentage in all content areas, indicating the effectiveness of structured teaching programmes. It was also shown that there is no significant relationship between pre-<br>test and post-test awareness scores and demographic characteristics.</p> <p><strong>Conclusion:</strong> The study’s findings demonstrated that structured teaching programmes were successful in improving awareness of the study subjects regarding HPV and its vaccine. Recommendations for future<br>research were proposed for the future based on the findings.</p> <p><strong>How to cite this article:</strong><br>Ansari N, Shaiju B, Hashmi S. A Pre-Experimental<br>Study to Assess the Effectiveness of Structured<br>Teaching Programme (STP) in Terms of<br>Awareness of Female Students Regarding Human<br>Papillomavirus (HPV) and its Vaccine in a Selected<br>School of New Delhi. Chettinad Health City Med<br>J. 2024;13(3):5-12.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202437<br><br></p> Nishat Ansari, Bindu Shaiju, Saba Hashmi Copyright (c) 2024 Nishat Ansari, Bindu Shaiju, Saba Hashmi https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2159 Mon, 30 Sep 2024 09:31:31 +0000 A Study on the Antibacterial and Cytotoxic Properties of Aqueous Extract of Terminalia chebula Fruits https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3065 <p>Introduction: The Combretaceae family species Terminalia chebula is frequently referred to as the “king of medicine” utilised throughout Tibet to treat a variety of conditions like diabetes, depression, leprosy, cardiovascular disease, inadequate memory etc due to its alluring antibacterial, antifungal, anticariogenic, anti-inflammatory, antimicrobial activity. Terminalia chebula fruits are rich in tannins, flavonoids, and essential oils.<br>Aim: To study the antibacterial and cytotoxic characteristics of Terminalia chebula aqueous extract<br>Method: Aqueous extracts of Terminalia chebula were tested using a brine-shrimp lethal assay for cytotoxicity and antimicrobial activity. In this present study on antibacterial activity, the effectiveness of T. chebula’s aqueous fruit extract against gram +ve and gram -ve bacteria (Staphylococcus aureus and Pseudomonas aeruginosa) was assessed using the Agar well diffusion method at different concentrations.<br>Results: Aqueous Terminalia chebula showed good effects as both antibacterial and cytotoxic using brine shrimp lethality assay.<br>Conclusion: Terminalia chebula aqueous extract showed an efficient antibacterial and cytotoxic effect and hence can be used for different biomedical applications.</p> <p><strong>How to cite this article:</strong><br>Azmathullah R, Dhanalakshmi P, Lakshmi K, Kumar S R. A Study on the Antibacterial and Cytotoxic Properties of Aqueous Extract of Terminalia chebula Fruits. Chettinad Health City Med J. 2024;13(3):13-17.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202438</p> Azmathullah R, Dhanalakshmi P, Lakshmi K, Rajesh Kumar S Copyright (c) 2024 Azmathullah R, Dhanalakshmi P, Lakshmi K, Rajesh Kumar S https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3065 Mon, 30 Sep 2024 00:00:00 +0000 A Study on the Impact of Endoscopic Myomectomy on Reproductive Outcomes of Assisted Reproductive Technology https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2353 <p><strong>Introduction:</strong> Uterine fibroids (myomas or leiomyomas) are the most common benign tumours in women of reproductive age. They have varied clinical presentations ranging from being asymptomatic to being a major source of clinical morbidity. The presence of uterine fibroids has been linked to fertility problems. <br><strong>Aims:</strong> The primary objective of the study is to evaluate the effect of endoscopic myomectomy on IVF outcomes in patients with fibroids in terms of pregnancy rate, implantation rate, and ongoing pregnancy rate. Miscarriage rates and ectopic and heterotopic pregnancy rates were also studied as secondary objectives. <br><strong>Method:</strong> This single-centre, retrospective observational study was conducted on patients with uterine myoma who visited Chennai Fertility Centre and Research Institute, Chennai for infertility treatment during <br>the period of June 2013 to June 2022.<br><strong>Statistical analysis used:</strong> The collected data was presented as a mean and standard deviation, frequency, or percentage. Pearson’s chisquare test was used to assess the association between IVF outcome and variables. Tests that were statistically significant at &lt; 0.05 were considered. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) software version 24.0.<br><strong>Results:</strong> The results showed higher ongoing pregnancy rates in the study group compared to the control group (68.89% vs. 42.2%) with a statistically significant difference in the p value (0.011). <br><strong>Conclusion:</strong> It can be concluded that endoscopic myomectomy, either laparoscopic or hysteroscopic, can be used as a treatment for submucosal and large (&gt; 4 cm) intramural fibroids and can improve the clinical pregnancy rate and cumulative implantation rate of infertile patients with fibroids.</p> <p><strong>How to cite this article:</strong><br>Nandi L, Sridev S, Thomas V M, Kulshrestha S, <br>Lakshmanan K, Abinaya R. A Study on the Impact <br>of Endoscopic Myomectomy on Reproductive <br>Outcomes of Assisted Reproductive Technology. <br>Chettinad Health City Med J. 2024;13(3):18-22.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202439</p> Lily Nandi, Smisha Sridev, Thomas VM, Shatakshi Kulshreshtha, Krishnavignesh Lakshmanan, Abinaya R Copyright (c) 2024 Lily Nandi, Smisha Sridev, Thomas VM, Shatakshi Kulshreshtha, Krishnavignesh Lakshmanan, Abinaya R https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2353 Mon, 30 Sep 2024 10:02:51 +0000 A Study to Assess the Awareness and Knowledge Related to Breast Cancer among Females in a Selected Area of Delhi https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2145 <p>Introduction: Breast cancer begins with uncontrolled breast cell growth and is classified by the type of cells involved. It usually starts in the breast ducts and can spread to other organs through blood or lymphatic vessels.<br>Methodology: This study used a quantitative approach with a descriptive survey research design. 100 women were chosen as subjects. A structured questionnaire was used to collect primary data through Google Forms. Descriptive statistics was employed to analyse the data.<br>Result: Results showed that 53% of the women didn’t know about the most prevalent cancer leading to death in women. The symptoms like palpable but painless breast lump, swelling under the armpit, and pain in the breast were reported by 77%, 65%, and 63% of subjects respectively. A total of 59% of subjects stated that breast cancer occurs in men as well and various risk factors mentioned by the participants were early menopause (36%), elderly primigravida (26%), changes in menstrual cycle (47%), etc. 99% did not know about the need of mammography after 40 years of age. An equal number of subjects were unaware of breast self-examination. Only 35% knew about chemotherapy and 73% about surgery as the treatment of cancer. None of the participants knew about radiation therapy. Post-survey, all women were educated about breast self-examination through lecture cum demonstration.<br>Conclusion: The study highlights a lack of breast cancer awareness, stressing the need for regular health education. Breast health programs can empower women to recognize risks and symptoms, leading to early detection and treatment of breast cancer.</p> <p><strong>How to cite this article:</strong><br>Negi A, Rani S. A Study to Assess the Awareness and Knowledge Related to Breast Cancer among Females in a Selected Area of Delhi. Chettinad Health City Med J. 2024;13(3):23-29.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202440</p> Arushi Negi, Seema Rani Copyright (c) 2024 Arushi Negi, Seema Rani https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2145 Mon, 30 Sep 2024 10:11:29 +0000 Availability of Toilet at the Household Level in India: Evidence from National Family Health Survey https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3071 <p>Introduction: Poor sanitation has an impact on all facets of human life, including health development, economy, dignity of a human being, nutrition and empowerment of individuals. Globally, one in ten people use open defecation and India has 564 million people who defecate in the open. The government of India is trying to eradicate open defecation by constructing individual household toilets through different sanitation programmes.<br>Methodology: This study analyses the sanitation conditions in India from 1992–93 to 2019–21. This study used five different rounds of the National Family Health Survey (NFHS) conducted in following years: NFHS-1 (1992–1993), NFHS-2 (1998–99), NFHS-3 (2005–06), NFHS-4 (2015–16), and NFHS-5 (2019–21).<br>Results: This study found that 69.3% of households had improved toilets, 8.4% had shared toilets, 2.9% had unimproved toilets and 19.4% did not have any toilet facility in 2019–21. This revealed that the individual household toilet facilities increased as a result of different sanitation programmes implemented by the government of India.<br>Conclusion: The last two decades highlight significant progress in improving access to adequate sanitation, driven by various government initiatives and policies. The data also reveals a shift towards more modern sanitation systems, such as flush toilets connected to piped sewer systems or septic tanks, indicating urbanisation and infrastructural development. This transition is crucial for public health, as it reduces the risk of waterborne diseases and improves overall well-being.</p> <p><strong>How to cite this article:</strong><br>Nirmalkumar K, Sivasankar V. Availability of Toilets at the Household Level in India: Evidence from National Family Health Survey. Chettinad Health City Med J. 2024;13(3):30-35.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202441</p> K NirmalKumar, V Sivasankar Copyright (c) 2024 K NirmalKumar, V Sivasankar https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3071 Mon, 30 Sep 2024 10:24:34 +0000 Does Wearing Heeled Footwear Have an Effect on Lower Back Function in Women?: A Cross-Sectional Study https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3090 <p><strong>Introduction:</strong> Pain is a concept that can occur due to many reasons. Females are more prevalent than males in terms of pain. The total occurrence of discomfort in the lower back is 28.8 % and thus the prevalence in females was 60.9% which is higher than in males which accounts for 39.1%. The important point that must be noted is the reports of many research studies showing that long-term usage of high-heeled footwear can adversely on various body parts. But still, women like to wear them.The foot, knee, and back pain are found to be 78.94% of women who wear &gt; 5 cm heel height and 53.12% of women who wear &lt; 5 cm heel height—back discomfort results from the user tipping their foot forward, which impacts pressure on their lower back. The negative impacts like low back ache, changes in gait, and sprain of the ankle were due to the increase in the curvature of the lumbar spine. <br><strong>Aim:</strong> The study aimed to analyse the correlation between high-heeled footwear usage and its impact on low-back mechanics. <br><strong>Method:</strong> This study was done for 100 female subjects wearing heeled footwear and the type of sampling was convenient sampling. The 100 female subjects are recruited based on the criterion of inclusion. Then the subjects were provided with informed consent before the study. They were provided with foot posture index (FPI) and Oswestry disability index (ODI). <br><strong>Results:</strong> Both descriptive and inferential statistics were used to tabulate and analyse the data that had been gathered. The Pearson Correlation Coefficient (r) has a value of 0.232. While there is a positive connection <br>and association between the Foot Posture Index (FPI) and the Oswestry Disability Index (ODI), women’s lower back discomfort worsens when their Foot Posture Index score (high-heeled footwear) increases. <br><strong>Conclusion:</strong> It is concluded that there is a significant association between foot posture and low back pain among women who wear heeled footwear. This can be used as a routine during the assessment for low-back pain.</p> <p><strong>How to cite this article:</strong><br>Swathi S R, Vardhini I C, Purushothaman S. <br>Does Wearing Heeled Footwear, Have an Effect <br>on Lower Back Function in Women?: A CrossSectional Study. Chettinad Health City Med J. <br>2024;13(3):36-41.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202442</p> Swathi S R, Ishwarya Vardhini C, Senthil Purushothaman Copyright (c) 2024 Swathi S R, Ishwarya Vardhini C, Senthil Purushothaman https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3090 Mon, 30 Sep 2024 10:32:23 +0000 Effect of Kinesio Taping on Spasticity and Postural Control in Stroke Patients with Hemiplegic Foot https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2795 <p><strong>Introduction:</strong> Post-stroke spasticity is a common complication of stroke and a key contributor to impaired Motor functions and functional independence. Patients with hemiplegic feet experience gait disturbances, impaired balances, and deviated posture control. <br><strong>Aim:</strong> The purpose of the study is to analyse the effect of Kinesio tape to reduce spasticity and improve postural control.<br><strong>Method:</strong> A comparative study with 60 subjects was conducted in Jaipur to analyse the effects of kinesio taping on spasticity and postural control. The subjects were divided into four groups, with Groups A and B focusing on spasticity and Groups C and D focusing on postural control. Statistical analysis was performed using the Modified Ashworth Scale and the Postural Assessment Scale for Stroke and Berg Balance Scale.<br><strong>Results:</strong> In a comparison among groups A and B, Group B showed a significant reduction in spasticity MAS (p = 0.001), and a comparison among groups C and D showed a significant difference in the K-taping group in BBS score (p = 0.001) and PASS scores (p = 0.001).<br><strong>Conclusion:</strong> According to the result, K-tape was effective in reducing spasticity and improving postural control, thus effectively promoting recovery in patients with hemiplegic feet after stroke.</p> <p><strong>How to cite this article:</strong><br>Gupta V, Khandelwal R, Jain A, Adha S. Effect <br>of Kinesio Taping on Spasticity and Postural <br>Control in Stroke Patients with Hemiplegic Foot. <br>Chettinad Health City Med J. 2024;13(3):42-46.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202443<br><br></p> Vidhi Gupta, Rakesh Khandelwal, Anjali Jain, Sudarshan Adha Copyright (c) 2024 Vidhi Gupta, Rakesh Khandelwal, Anjali Jain, Sudarshan Adha https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2795 Mon, 30 Sep 2024 10:38:33 +0000 Efficacy of Muscle Energy Technique Versus Movement with Mobilisation in Recreational Swimmers with Scapular Dyskinesis: A Comparative Study https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3082 <p>Introduction: Recreational swimming is a popular all-around exercise that is particularly helpful in therapy and as an exercise for people. In recreational swimming, repetitive arm revolutions put a significant amount of musculoskeletal strain on the shoulder complex, which might affect the shoulder’s kinematics. Loss of control over the typical scapular mechanics, physiology, and motion is known as dyskinesis. This can cause pain while resting, as well as during activities, and is the most commonly noted location of orthopaedic injury in swimmers.<br>Objective of the study: The objective of the current research was to assess the efficiency of MET vs MWM in recreational swimmers with SD.<br>Method: It was a randomised comparative trial. When the subjects were split into 2 groups, Group MET (n = 16) received MET and scapular kinematic exercise and Group MWM (n = 19) received MWM and scapular kinematic exercise. Both groups received therapy for four weeks. The outcome measures were evaluated through LSST and DASH score Dash Sports Module.<br>Result: Pre and post values of LSST, DASH score, and DASH sports module decreased in both groups (p value &lt; 0.05).<br>Conclusion: The research concluded that both MWM and MET showed efficiency in correcting SD. However, MET with exercise was found to be more effective in improving SD in swimmers.</p> <p><strong>How to cite this article:</strong><br>Sangma K, Das L. Efficacy of Muscle Energy Technique Versus Movement with Mobilisation in Recreational Swimmers with Scapular Dyskinesis: A Comparative Study. Chettinad Health City Med J. 2024;13(3):47-54.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202444</p> Karma Sangma, Lopa Das Copyright (c) 2024 Karma Sangma, Lopa Das https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3082 Mon, 30 Sep 2024 10:56:56 +0000 Efficacy of Rapid Inspiratory Bouts Followed by Sustained Expiration on Maximal Force Generation During Isometric Exercise https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2778 <p>Introduction: Isometric is a static type of exercise in which the strength of muscle is increased due to an increase in tension in the muscle fibres, but many health professionals are against the use of isometrics due to<br>its adverse effect on the cardiovascular system.<br>Objective: The objective of the current research is to examine the impact of rapid inspiratory bouts followed by sustained expiration on maximal force generation during isometrics.<br>Methodology: Forty patients with lower limb weakness performed rapid inspiratory bouts followed by sustained expiration while performing isometrics of the quadriceps and hamstrings muscle group. The strength<br>of patients was measured by a hydraulic hand dynamometer. This study assessed pre- and post-isometric results. In the pre-session, participants were asked to do 10 repetitions of isometrics of the quadriceps and<br>hamstring muscle group according to their own method. Then after 10 minutes, they were taught to take several gulps of inspiration and to expire in a controlled way while exerting force on a dynamometer. The mean of all repetitions was calculated.<br>Results: On comparing the two sessions, the maximal force generation was increased in the quadriceps muscle group (p &lt; 0.001) and hamstrings (p &lt; 0.001) while doing isometrics with the use of rapid inspiratory bouts followed by sustained expiration while doing isometrics.<br>Conclusion: Therefore the study concludes that taking rapid inspiratory bouts followed by sustained expiration has a significant effect on the strength of muscles.</p> <p><strong>How to cite this article:</strong><br>Shinde A, Nikam P. Efficacy of Rapid Inspiratory<br>Bouts Followed by Sustained Expiration on<br>Maximal Force Generation During Isometric<br>Exercise. Chettinad Health City Med J.<br>2024;13(3):55-58.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202445</p> Asmita Shinde, Prasannajeet Nikam Copyright (c) 2024 Asmita Shinde, Prasannajeet Nikam https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2778 Mon, 30 Sep 2024 11:07:36 +0000 Exploring the Relationships among Mobile Phone Addiction, Academic Procrastination, and Academic Performance in Nursing Education https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3070 <p>Introduction: Medical education plays a crucial role in preparing qualified healthcare professionals, and academic achievement is essential for students’ success. However, academic procrastination and mobile phone addiction have been identified as challenges that can negatively impact students’ academic performance. This study aimed to explore the relationships among mobile phone addiction, academic procrastination, and academic accomplishment specifically among nursing students.<br>Method: A correlational research design was applied in this study. A sample of 121 nursing students from Tirupati College of Nursing, Udaipur was recruited using a convenience sampling technique. Validated self-report questionnaires were utilised to assess mobile phone addiction, academic procrastination tendencies, and academic accomplishment. The data were analysed using appropriate statistical methods, including correlation analysis and regression analysis.<br>Results: The results show a positive correlation between mobile phone addiction and academic procrastination among nursing undergraduates. However, there was no significant direct effect of mobile phone addiction on academic accomplishment. The study also identified an adverse association between academic procrastination and academic accomplishment, emphasising the detrimental impact of procrastination on students’ academic performance.<br>Conclusion: The findings suggest that nursing students who experience higher levels of mobile phone addiction may have an increased tendency to procrastinate academically. While mobile phone addiction did not directly impact academic achievement, academic procrastination was found to have a negative influence on academic performance. These results underscore the importance of addressing procrastination tendencies among nursing students to improve their academic success.</p> <p><strong>How to cite this article:</strong><br>Rajpurohit L, Yadav K C. Exploring the Relationships among Mobile Phone Addiction, Academic Procrastination, and Academic Performance in Nursing Education. Chettinad Health City Med J. 2024;13(3):59-64.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202446</p> Lalit Rajpurohit, KC Yadav Copyright (c) 2024 Lalit Rajpurohit, KC Yadav https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/3070 Mon, 30 Sep 2024 11:18:51 +0000 Improving the Dissolution Characteristics of Itraconazole by Formulating Cocrystal with the Use of Appropriate Conformers Using Solvent Evaporation Method https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2622 <p>Introduction: Itraconazole BCS class II drugs have low solubility. Their solubility improves made cocrystal. Cocrystals can be made by many methods like solvent evaporation, cooling crystallisation, and freeze-drying.<br>Method: In this study, cocrystals were prepared by slow solvent evaporation method with the use of an appropriate coformer with a suitable stoichiometric ratio and COSMO-RS software. Itraconazole and the coformer were dissolved in the proper solvent or solvent mixture and swirled on a magnetic stirrer for 45 minutes at 600 rpm until the product was totally dry. Cocrystal characterisation was done on this product. To create cocrystals, organic acid coformers such as benzoic acid, salicylic acid, caffeine, oxalic acid, and nicotinamide were utilised. Prepared cocrystals were evaluated on the basis of FTIR spectra, DSC thermogram, powder X-ray diffraction, in vitro dissolution study and saturation solubility study.<br>Results: The FTIR, DSC, and PXRD results indicated that there was no cocrystallisation in organic acid coformers. The usage of amino acids such as glycine, alanine, cysteine, and proline followed. Of these, glycine and alanine showed promise in FTIR, DSC, PXRD, saturation solubility research, and in vitro dissolution studies. Alanine and oxalic acid showed promising results in powder X-ray diffraction.<br>Conclusion: In the current study, itraconazole cocrystals were effectively created by slow solvent evaporation and had better-dissolving properties than pure itraconazole. Additionally, it was shown that the manufactured cocrystal had a greater saturation solubility than pure itraconazole. Co-crystallisation is therefore a viable method to enhance medication solubility properties without compromising structural integrity and pharmacological effectiveness.</p> <p><strong>How to cite this article:</strong><br>Kanabar V, Radadiya J, Gadhiya H. Improving the Dissolution Characteristics of Itraconazole by Formulating Cocrystal with the Use of Appropriate Conformers Using Solvent Evaporation Method. Chettinad Health City Med J. 2024;13(3):65-74.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202447</p> Vishvesh Kanabar, Jayesh Radadiya, Harshil Gadhiya Copyright (c) 2024 Vishvesh Kanabar, Jayesh Radadiya, Harshil Gadhiya https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2622 Mon, 30 Sep 2024 11:30:35 +0000 Virtual Teaching Tool on Post-Disaster Adolescents’ Quality of Life Affected by Flood in Uttarakhand https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2674 <p><strong>Introduction:</strong> Recurrent floods leave behind a terrible death toll, destroyed homes, destroyed food and crops, and a low quality of life. Thus, the purpose of this study was to evaluate how well the virtual teaching tool (VTT) improved the quality of life (QOL) of adolescents who had been affected by flooding in Uttarakhand.<br><strong>Method:</strong> A quasi-experimental study, including 417 adolescents aged 10–19 years who were affected by the flood at Rudraprayag and Uttarkashi, Uttarakhand were recruited using a purposive sampling technique; out of which, 400 adolescents participated successfully. Data were collected using self-structured sociodemographic variables and WHOQOL-BREF 26 items. VTT to improve QOL was administered after the pre-test.<br><strong>Results:</strong> A notable proportion of adolescents were unemployed (65.75%) and came from families with a monthly income of less than INR 10,000 (77%). Despite these challenges, there was a significant improvement <br>in their quality of life based on WHOQOL-BREF scores: post-test mean ± SD score was 93.932 ± 9.134, compared to the pre-test mean ± SD score of 86.775 ± 10.481, significant at p &lt; 0.05. Quality of life was significantly associated with age, religion, education, employment status, and habitation.<br><strong>Conclusion:</strong> Adolescents affected by the flood had a low quality of life in the pre-test, but the administration of VTT was found to be beneficial in improving QOL in the post-test.</p> <p><strong>How to cite this article:</strong><br>Devnarayan. Virtual Teaching Tool on PostDisaster Adolescents’ Quality of Life Affected <br>by Flood in Uttarakhand. Chettinad Health City <br>Med J. 2024;13(3):75-86.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202448</p> Devnarayan Copyright (c) 2024 Devnarayan https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2674 Mon, 30 Sep 2024 12:57:15 +0000 A Brief Review on Smart Drug Design in Favour of Improving Health Indicator https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/1950 <p>The drug is a vital need in contemporary scenarios. Relevant to the traditional methods of drug designing like structural-based drug design and computer-aided drug design, Molecular Docking (MD) is a more complicated and intelligent tool. Approaching the precise three-dimensional binding site or pose of the drug candidate with the receptor is the target of ligand-receptor docking. It calculates the preciseness of drug candidates with receptors. Lead optimisation is assessed by the combinatorial libraries and provides the beneficial or harmful consequences of drug-receptor interaction. It can be difficult to interpret the outcomes of stochastic search methods and establishing the input structures for docking is just as important as docking itself. Based on the system’s overall energy, docking simulations forecast an optimum docked conformer. Despite all viable strategies, the difficulties still lay in ligand chemistry like tautomerism and ionisation, the rigidity of receptors like multi-confirmation of the drug candidate for the same receptor, and the interaction of the drug with the precise binding site. This article briefly discusses a few significant features of MD, including its techniques, kinds, applications, and problems.</p> <p><strong>How to cite this article:</strong><br>Kumar V, Dobhal K, Guleria I, Bhawna, Rautela J. A Brief Review on Smart Drug Design in Favor of Improving Health Indicator. Chettinad Health City Med J. 2024;13(3):87-98.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202449</p> Vikrant Kumar, Kiran Dobhal, Itika Guleria, Bhawna, Jaya Rautela Copyright (c) 2024 Vikrant Kumar, Kiran Dobhal, Itika Guleria, Bhawna, Jaya Rautela https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/1950 Mon, 30 Sep 2024 12:09:32 +0000 An Analysis of Medicinal Plants in the Management of Male Infertility https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2666 <p>Infertility, coupled with issues related to sexual dysfunction, has long been a pressing global concern, affecting approximately 15% of couples. Interestingly, males shoulder the sole responsibility, which results in 20–30% of cases of fertility problems. Current strategies to tackle infertility often come at a substantial financial cost and carry the risk of various enduring adverse effects. The causes of male infertility span a broad spectrum, encompassing both quantitative and qualitative declines in semen quality. What has consistently piqued the interest of both medical professionals and researchers is the utilisation of herbal remedies, which possess a firmly established scientific basis for combating infertility. This review is dedicated to exploring the medicinal plants that have been documented in ancient texts and have since garnered scientific validation. These plants have demonstrated their effectiveness in enhancing male reproductive health and are recommended for addressing male infertility.</p> <p><strong>How to cite this article:</strong><br>Khadar B A A, Suganthi V. An Analysis of Medicinal Plants in the Management of Male Infertility. Chettinad Health City Med J. 2024;13(3):99-108.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202450</p> Abdul Khadar BA, Suganthi V Copyright (c) 2024 Abdul Khadar BA, Suganthi V https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2666 Mon, 30 Sep 2024 12:36:50 +0000 Muscular Cysticercosis Presenting with Right Side Foot Drop – A Case Study https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2222 <p>Cysticercosis is a parasitic infection caused by the larvae of the tapeworm Taenia solium. It can manifest as either neural or extraneural forms. Extra neural forms commonly involve eyes, skeletal muscles and subcutaneous tissue in the form of a single or multiple submucosal or subcutaneous firm nodules. This single case study is a rare case of muscular cysticercosis affecting the tibialis anterior muscle causing compression of the deep peroneal nerve causing foot drop. This study is to prove the efficacy of functional electrical stimulation along with modified exercise therapy, and ankle foot orthosis (AFO) for management of foot drop. A 42-year-old man presented with a case of foot drop. He was initially treated in the Department of General Surgery and was diagnosed with cysticercosis of the tibialis anterior muscle, which caused compression in the deep peroneal nerve and resulted in foot drop. The subject presented with severe weakness and paralysis of the right foot dorsiflexor muscles, resulting in significant gait impairment and balance issues. He was treated with anthelminthic and nonsteroidal anti-inflammatory drugs (NSAIDs) and physiotherapy management. A four-week physiotherapy intervention was administered, comprising functional electrical stimulation, AFO, muscle strengthening, proprioceptive exercises, and gait training. The results demonstrated substantial improvements in gait, functional mobility, and dorsiflexion power from 1 to 4 in MRC grading and from 38% to 90% in FADI score suggesting the beneficial impact of physiotherapy in managing foot drop following muscular cysticercosis. This case study sheds light on the potential effectiveness of physiotherapeutic interventions with medications in enhancing motor function and quality of life in subjects with foot drop resulting from this rare parasitic infection.</p> <p><strong>How to cite this article:</strong><br>Nainar A M, Babu L H, Fathima M M Z, Kowsigan K, Karthik M C, Bharathi V. Muscular Cysticercosis Presenting with Right Side Foot Drop – A Case Study. Chettinad Health City Med J. 2024;13(3):109-113.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202451</p> Mohamed Nainar A, Hari Babu L, Mohamed Zerein Fathima M, K Kowsigan, MC Karthik, Vijaya Bharathi Copyright (c) 2024 Mohamed Nainar A, Hari Babu L, Mohamed Zerein Fathima M, K Kowsigan, MC Karthik, Vijaya Bharathi https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2222 Mon, 30 Sep 2024 12:53:57 +0000 Insured Health System: A Potential Solution for a Sustainable Healthcare Future https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2108 <p><strong>How to cite this article:</strong><br>Raja T K, Senthila M. Insured Health System: <br>A Potential Solution for a Sustainable <br>Healthcare Future. Chettinad Health City Med <br>J. 2024;13(3):114-115.</p> <p><strong>DOI:</strong> https://doi.org/10.24321/2278.2044.202452</p> Raja T K, Senthila M Copyright (c) 2024 Raja T K, Senthila M https://medical.advancedresearchpublications.com/index.php/CHCMJ/article/view/2108 Mon, 30 Sep 2024 12:55:55 +0000