In vitro Antibacterial Activity of Alangium salvifolium and Alangium lamarckii against Human Pathogenic Bacterial Species
Abstract
Introduction: The plants Alangium salvifolium and Alangium lamarckii have been utilised to treat various ailments in traditional folk medicine. The current study aims to examine the antibacterial efficacy of extracts of bark of Alangium salvifolium and Alangium lamarckii.
Methods: In this study, the extracts of bark of selected plants using solvents methanol, ethanol and petroleum ether were subjected to evaluation of their antibacterial activity. The serial dilution method was employed to determine the minimum inhibitory concentration (MIC) for each plant extract. The agar well diffusion method was used to assess antibacterial activity against clinically significant gram-positive and gram-negative bacterial strains, including Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis,
and Enterobacter cloacae.
Results: The methanolic extract of the bark of Alangium salvifolium and Alangium lamarckii exhibited the maximum antibacterial effect when compared with the ethanolic and petroleum ether extracts. The methanolic extract of the bark of A. salvifolium showed the maximum zone of inhibition of 26.07 ± 1.31 mm against Pseudomonas aeruginosa. Methanolic extract of bark of A. lamarckiishowed the maximum zone of inhibition 27.00 ± 1.20 mm against Pseudomonas aeruginosa.
Conclusion: Therefore, the bark extracts of Alangium salvifolium and Alangium lamarckii exhibited an antibacterial effect against selected human bacterial pathogens. So, the present study concluded that both of these plants may serve as prospective source materials for the development of new antibacterial agents.
How to cite this article: c, Bharathi T, Saravanan M, Udayakumar R. In vitro Antibacterial Activity of Alangium salvifolium and Alangium lamarckii against Hum an Pathogenic Bacterial Species. Chettinad Health City Med J.
2025;14(1):51-58.
DOI: https://doi.org/10.24321/2278.2044.202508
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