Anti-Bacterial Activity of Homoeopathic Nosodes Anthracinum, Pyrogenium and Variolinum in 30 C, 200 C and 1 M Potencies Against Methicillin Resistant Staphylococcus Aureus - An In Vitro Study
Abstract
Introduction: The homoeopathic system of medicine is still considered as pseudoscience by the scientific community due to the lack of material substance in highly diluted medicinal formulations, despite clinical results. On the other hand, biomedicine is threatened by antimicrobial resistance against various pathogens. Methicillin-Resistant Staphylococcus aureus (MRSA), a virulent strain of the bacteria Staphylococcus aureus, is resistant to several antibiotics like methicillin, nafcillin, oxacillin, and cephalosporins. In this study, homoeopathic nosodes also called biotherapeutic preparations, which are homoeopathic preparations made from pure microbiological cultures isolated from sick tissue and clinical samples like secretions, discharges, etc., were tested against MRSA to understand its antibacterial effects.
Method: Homoeopathic nosodes Anthracinum, Pyrogenium and Variolinum each in three different potencies namely 30 C, 200 C and 1 M were tested against MRSA by standardised Kirby–Bauer disk diffusion technique. Antibiotic vancomycin and dispensing alcohol were used as positive and negative control respectively.
Result: After the study, it was found that homoeopathic nosode Pyrogenium 200 C, Pyrogenium 1 M and Athracinum 200 C showed maximum inhibition zones of 11 mm, 10 mm and 10 mm respectively.
Conclusion: The results of this study indicate the efficacy of highly diluted homoeopathic medicines against the most virulent and threatening MRSA.
How to cite this article:
Simi P S, Mary B H, Priyashree R, Maalolan S, Mol R S R. Anti-Bacterial Activity of Homoeopathic Nosodes Anthracinum, Pyrogenium and Variolinum in 30 C, 200 C and 1 M Potencies Against Methicillin Resistant Staphylococcus Aureus - An In Vitro Study. Chettinad Health City Med J. 2024;13(1):20-24.
DOI: https://doi.org/10.24321/2278.2044.202404
References
Wikipedia [Internet]. Homeopathy; 2019 Nov 17 [cited 2023 Jun 24]. Available from: https://en.wikipedia.org/wiki/Homeopathy
Wikipedia [Internet]. Biomedicine; 2020 May 1 [cited 2023 Jun 26]. Available from: https://en.wikipedia.org/wiki/Biomedicine
World Health Organization [Internet]. Antibiotic resistance; 2020 Jul 31 [cited 2023 Jun 24]. Available from: https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance#:~:text=Antibiotic%20resistance%20occurs%20when%20bacteria,caused%20by%20non%2Dresistant%20bacteria
Moses VK, Kandi V, Rao SK. Minimum inhibitory concentrations of Vancomycin and Daptomycin against Methicillin-resistant Staphylococcus aureus isolated from various clinical specimens: a study from South India. Cureus [Internet]. 2020 [cited 2023 Jun 25];12(1):e679. Available from: https://doi.org/10.7759/cureus.6749 [PubMed] [Google Scholar]
Taylor TA, Unakal CG. Staphylococcus aureus infection [Internet]. StatPearls Publishing; 2022 [cited 2023 Jun 29]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441868/ [PubMed] [Google Scholar]
Siddiqui AH, Koirala J. Methicillin-Resistant Staphylococcus aureus [Internet]. StatPearls Publishing; 2023 [cited 2023 Jun 27]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482221/ [PubMed] [Google Scholar]
Rottler G. [Nosodes nowadays=nosodes of the past? Discussion of sources and methods of preparation]. Allgem Homöop Zeit [Internet]. 2005 [cited 2023 Jun 27];250(2). Available from: https://doi.org/10.1055/s-2005-868692. German. [Google Scholar]
Clarke JH. A clinical repertory to the dictionary of Materia Medica. CW Daniel Company Limited; 1995.
Sarker MM, Islam KN, Huri HZ, Rahman M, Imam H, Hosen MB, Mohammad N, Sarker MZ. Studies of the impact of occupational exposure of pharmaceutical workers on the development of antimicrobial drug resistance. J Occup Health [Internet]. 2014 [cited 2023 Jun 29];56(4):260-70. Available from: https://doi.org/10.1539/joh.14-0012-oa [PubMed] [Google Scholar]
National Center for Complementary and Integrative Health [Internet]. Homeopathy: what you need to know; 2021 Apr [cited 2023 Jun 29]. Available from: https://www.nccih.nih.gov/health/homeopathy