Evaluation of the Antibacterial Activity of Eucalyptus Globulus 3C and 6C against Uropathogens

Maalolan S; Priyashree R; Sisir PR; Chandraja CV; Gopukumar ST

Maalolan S PG Scholar, Department of Paediatrics, Sarada Krishna Homoeopathic Medical College (Affiliated to The Tamil Nadu Dr MGR Medical University, Chennai), Kulasekharam, Kanyakumari District, Tamil Nadu, India.
Priyashree R PG Scholar, Department of Paediatrics, Sarada Krishna Homoeopathic Medical College (Affiliated to The Tamil Nadu Dr MGR Medical University, Chennai), Kulasekharam, Kanyakumari District, Tamil Nadu, India.
Sisir PR Professor & Head, Department of Paediatrics, Sarada Krishna Homoeopathic Medical College (Affiliated to The Tamil Nadu Dr MGR Medical University, Chennai), Kulasekharam, Kanyakumari District, Tamil Nadu, India.
Chandraja CV Former Research Officer, Research Facilitation Center, Sarada Krishna Homoeopathic Medical College, Kulasekharam, Tamil Nadu, India.
Gopukumar ST Research Associate, Research Facilitation Center, Sarada Krishna Homoeopathic Medical College, Kulasekharam, Tamil Nadu, India.

Keywords: Eucalyptus Globulus, Zone Of Inhibition, Drug Resistance, Empirical Treatment

Abstract

Introduction: Infections of the urinary tract are one of the most
frequently encountered problems reported in outpatient settings. In
the majority of the instances, clinicians initiate empirical antimicrobial
therapy before the laboratory results of urine culture are available.
This happens to be one of the most prominent causes of resistance to
antibiotics in diverse uropathogens. These microbes can cause a new
form of infectious disease because of this drug resistance and may
become more resistant because of mutation after some time.
Methods: The purpose of this study was to assess the antimicrobial
properties of Eucalyptus globulus 3C and 6C directed at typical bacterial
strains of Pseudomonas aeruginosa, Escherichia coli and Proteus
mirabilis. The broth culture of the above organisms was prepared
and colonies were allowed to be formed, following which, the zones
of inhibition and minimum inhibitory concentrations were determined
across each of the bacterial strains.
Results: In this study, the medicine Eucalyptus globulus 3C and 6C
demonstrated significant antimicrobial properties against Pseudomonas
aeruginosa and Escherichia coli.
Conclusion: In this in vitro study, Eucalyptus globulus 3C and 6C showed
a maximum zone of inhibition of about 9 mm and 12 mm against
Escherichia coli.

How to cite this article:
Maalolan S, Priyashree R, Sisir PR, Chandraja CV,
Gopukumar ST. Evaluation of the Antibacterial
Activity of Eucalyptus Globulus 3C and 6C against
Uropathogens. Chettinad Health City Med J.
2023;12(4):53-57.

DOI: https://doi.org/10.24321/2278.2044.202372

References

Ruppé É, Woerther PL, Barbier F. Mechanisms of antimicrobial resistance in gram-negative bacilli. Ann Intensive Care. 2015 Dec;5(1):61. [PubMed] [Google Scholar]

Li XZ, Plésiat P, Nikaido H. The challenge of effluxmediated antibiotic resistance in gram-negative bacteria. Clin Microbiol Rev. 2015 Apr;28(2):337-418. [PubMed] [Google Scholar]

Shanson DC. Microbiology in clinical practice. Elsevier Science; 2014. p. 430-7. [Google Scholar]

Coast J, Smith RD, Miller MR. Superbugs: should antimicrobial resistance be included as a cost in economic evaluation? Health Econ. 1996;5(3):217-26. [PubMed] [Google Scholar]

Pulingam T, Parumasivam T, Gazzali AM, Sulaiman AM, Chee JY, Lakshmanan M, Chin CF, Sudesh K. Antimicrobial resistance: prevalence, economic burden, mechanisms of resistance and strategies to overcome. Eur J Pharm Sci. 2022 Mar 1;170:106103. PubMed] [Google Scholar]

Jamison DT, Frenk J, Knaul F. International collective action in health: objectives, functions and rationale. Lancet. 1998;351(9101):514-7. [PubMed] [Google Scholar]

Boericke W. New manual of homoeopathic materia medica and repertory. B Jain Publishers; 2002. [Google Scholar]

Murphy R. Lotus materia medica. B Jain Publishers; 2003.

Rehman A, Shaffique S, Ahmed S, Anwar H, Hussain G, Asif HM, Javed S. Comparative analysis of antibacterial activity of ciprofloxacin and homeopathic mother tincture. RADS J Pharm Pharm Sci. 2018 Jun 20;6(2):113-8. [Google Scholar]

Ghalem BR, Mohamed B. Antibacterial activity of leaf essential oils of Eucalyptus globulus and Eucalyptus camaldulensis. Afr J Pharm Pharmacol. 2008;2(10):211-5. [Google Scholar]

Hafsa J, ali Smach M, Khedher MR, Charfeddine B, Limem K, Majdoub H, Rouatbi S. Physical, antioxidant and antimicrobial properties of chitosan films containing Eucalyptus globulus essential oil. LWT Food Sci Technol. 2016;68:356-64. [Google Scholar]

Varma PN, Vaid I. Encyclopaedia of homoeopathic pharmacopoeia. Vol IB. B Jain Publishers; 2002. p. 654-7.

Chandorkar N, Tambe S, Amin P, Madankar C. A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus. Phytomed Plus. 2021;1(4):100089. [Google Scholar]

Elangovan S, Mudgil P. Antibacterial properties of Eucalyptus globulus essential oil against MRSA: a systematic review. Antibiotics (Basel). 2023 Feb 27;12(3):474. [PubMed] [Google Scholar]