A Cross-sectional Observational Study to Assess Clinical Characteristics, Prescription Patterns and Health-related Quality of Life in Patients with Migraine at a Tertiary Care Teaching Hospital
Introduction: Many people around the world suffer greatly from migraine.
It is critical to comprehend the clinical nuances, therapeutic approaches,
and wider quality-of-life concerns that affect these patients.
Objectives: The present study was focused on assessing the clinical
characteristics which include the symptom profile, triggering factors,
prescription pattern, headache-related disability, and its impact on
patients’ health-related quality of life (HRQoL).
Methods: A cross-sectional observational study was conducted from
October 2019 to March 2020 at the Department of Neurology, Dhiraj
General Hospital, Vadodara. The data were collected from patients’
medical records and through counselling the patients who visited the
Out-Patient Department (OPD) or In-Patient Department (IPD). All patients
who met the inclusion criteria were enrolled in the study.
Results: The incidence of migraine was found to be higher in females
(78%) as compared to males (22%). The majority of patients had a severe
disability and severe impact on HRQoL with high MIDAS (Migraine
Disability Assessment Scale) and HIT-6 (Headache Impact Test-6) scores.
A majority of patients gained less score showing poor quality of life with
MSQoL v2.1 [Migraine Specific Quality of Life (version 2.1)]. A higher
MIDAS score was observed in chronic migraineurs than episodic migraineurs
while HIT-6 showed a comparable score. Unlike MIDAS and
HIT-6, MSQoL v2.1 showed lower scores in chronic migraineurs than
episodic migraineurs which depicts that chronic migraineurs had a poor
health-related quality of life than episodic migraineurs.
Conclusion: Healthcare professionals should routinely evaluate the
quality of life and related disability to determine whether patients are
receiving effective treatment and if any additional treatment strategies
are warranted to enhance QOL.
How to cite this article:
Kapadi VD, Parekh KS. A Cross-sectional
Observational Study to Assess Clinical
Characteristics, Prescription Patterns and Healthrelated
Quality of Life in Patients with Migraine
at a Tertiary Care Teaching Hospital. Chettinad
Health City Med J. 2023;12(3):9-20.
Medical News Today [Internet]. Why do I have a headache? Causes, types, and remedies; 2020 [cited 2022 Mar 10]. Available from: http://www.medicalnewstoday.com/articles/73936.php
Sajobi TT, Amoozegar F, Wang M, Wiebe N, Fiest KM, Patten SB, Jette N. Global assessment of migraine severity measure: preliminary evidence of construct validity. BMC Neurol. 2019;19(1):53. [PubMed] [Google Scholar]
Medscape [Internet]. Migraine headache; 2020 [cited 2022 Mar 14]. Available from: http://medscape.com/article/1142556-overview
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1211-59. [PubMed] [Google Scholar]
GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(5):459-80. [PubMed] [Google Scholar]
Bartelson JD, Cutrer FM. Migraine update. Diagnosis and treatment. Minn Med. 2010 May;93(5):36-41. [PubMed]
Wikipedia [Internet]. Quality of life; 2020 [cited 2022 Apr 14]. Available from: https://en.wikipedia.org/wiki/Quality of life
Centers for Disease Control and Prevention (US) [Internet]. HRQOL concepts; 2020 [cited 2022 Jun 13]. Available from: https://www.cdc.gov/hrqol/concept.htm
Martelletti P, Schwedt TJ, Lanteri-Minet M, Quintana R, Carboni V, Diener HC, la Torre ER, Craven A, Rasmussen AV, Evans S, Laflamme AK, Fink R, Walsh D, Dumas P, Vo P. My migraine voice survey: a global study of disease burden among individuals with migraine for whom preventive treatments have failed. J Headache Pain. 2018;19(1):115. [PubMed] [Google Scholar]
Steiner TJ, Stovner LJ, Birbeck GL. Migraine: the seventh disabler. Cephalalgia. 2013;33(5):289-90. [PubMed] [Google Scholar]
Leonardi M, Raggi A. A narrative review on the burden of migraine: when the burden is the impact on people’s life. J Headache Pain. 2019;20(1):41. [PubMed] [Google Scholar]
Shin HE, Park JW, Kim YI, Lee KS. Headache Impact Test-6 (HIT-6) scores for migraine patients: their relation to disability as measured from a headache diary. J Clin Neurol. 2008;4(4):158-63. [PubMed] [Google Scholar]