Efficacy of Ethanolic Extracts for Two Plants on Wound Healing in Diabetic Albino Rats

  • Girish Kumar Vyas Research Scholar, School of Pharmaceutical Studies, Faculty of Health Sciences, Dr K.N. Modi University, Newai, Rajasthan, India.
  • Hariom Sharma Professor, School of Pharmaceutical Studies, Faculty of Health Sciences, Dr K.N. Modi University, Newai, Rajasthan, India.
  • Bhupendra Vyas Head & Associate Professor, Department of Pharmacognosy, BN Institute of Pharmaceutical Sciences, Bhupal Nobles’ University Udaipur, Rajasthan, India.
  • Anil Sharma Asscociate Professor, School of Pharmaceutical Studies, Faculty of Health Sciences, Dr K.N. Modi University, Newai, Rajasthan, India.
  • Manmohan Sharma Asscociate Professor, School of Pharmaceutical Studies, Faculty of Health Sciences, Dr K.N. Modi University, Newai, Rajasthan, India.
Keywords: Diabetes, Healing, Extraction, Contraction, Epithelialization


Background: Wounds in diabetic patients are critical to treat. The use of allopathic drugs has various side effects, hence new natural sources for therapies are vital.

Materials and Methods: This research aimed to determine the possibility of wound healing by the ethanolic extract of Eucalyptus globulus leaves and Curcuma longa rhizomes. Albino rats were given oral administration of various plant extracts in order to find out how plant extracts affected diabetic rats’ wound healing.

Results: These plant extracts greatly accelerated the wound’s ability to heal in diabetic or non-diabetic rats (p < 0.05). This increases the proliferation and migration of the fibroblast resulting in a faster healing process. These plant extracts do not cause cytotoxicity. After treatment, less amount of cell death was found for both plant extracts. The results were found to be positive.

Conclusion: This research indicates that the ethanolic extracts of both plants have the potential to be used as novel therapeutics for diabetic patients’ wound healing.

How to cite this article:
Vyas GK, Sharma H, Vyas B, Sharma A, Sharma M. Efficacy of Ethanolic Extracts for Two Plants on Wound Healing in Diabetic Albino Rats. Chettinad Health City Med J. 2023;12(2):46-55.

DOI: https://doi.org/10.24321/2278.2044.202327



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