OUTCOME OF SKIN SENSITIVITY TEST FOR ASSESSING ADVERSE REACTIONS TO EQUINE RABIES IMMUNOGLOBULIN IN A TERTIARY SETUP OF SOUTH ODISHA

Abstract

Rabies immunoglobulin is life saving in patients exposed to Rabies virus. Despite
the high degree of purification of equine rabies immunoglobulin, the
manufacturer still recommends a skin sensitivity test before administration of
this heterologous serum. A recent WHO recommendation states that there is no
scientific ground for performing a skin test before administrating ERIG because
testing does not predict reaction so it should be given irrespective of the test
results. So we assessed the value of skin sensitivity testing in predicting adverse
reactions to ERIG.