A Case Report: Forced Alkaline Diuresis in a Case of 2, 4 D Dimethyl-Amine Herbicide Poisoning

Mon, 19 May 2025 06:20:51 +0000

To study the use of 2, 4 D is increasing because of resistance emerging
in Paraquat and Glycophosphate for weed control, hence accidental
or suicidal intoxication incidences are rising. Action of this is dose
dependent with detrimental effects on cell membrane of Acetyl - CoA
metabolism and oxidative phosphorylation.
It is fatal if not treated timely, having no specific antidote involving
CNS, CVS, RS, Hepatoblliary, muscle and endocrine systems. Usually,
it is very common with intoxication of organophospate compounds in
India, similar to alcohol, sedative drugs, aromatic compounds which is
suspected when patient comes to emergency room. So, Identification
of correct compound for timely management can be lifesaving.
Prolonged Coma, Metabolic complications, Skeletal muscle complication
are some of the complications of 2 4 D. Treatment with forced alkaline
diuresis is life saving measure in resource limited rural area where
hemodialysis is not available.

How to cite this article:
Gupta S, Deshmukh R, Deshpande S, Patki S,
Akotkar S, Suradkar P. A Case Report : Forced
Alkaline Diuresis in a Case of 2, 4 D Dimethyl
Amine Herbicide poisoning. J Adv Res Med 2025;
12(1): 1-3.

DOI: https://doi.org/10.24321/2349.7181.202501

Journal of Advanced Research in Medicine (E-ISSN: 2349-7181 & P-ISSN: 2394-7047)

A Case Report: Forced Alkaline Diuresis in a Case of 2, 4 D Dimethyl-Amine Herbicide Poisoning