Current Pattern and Clinico-Bacteriological Profile of Healthcare Associated Infections in an ICU Setting: A Study from a Tertiary Care Centre in Delhi

  • Naresh Kumar Department of Medicine, Maulana Azad Medical College, New Delhi, India. https://orcid.org/0000-0003-4581-609X
  • Saman Wasi Department of Medicine, Maulana Azad Medical College, New Delhi, India.
  • Mradul Kumar Daga Internal Medicine and Infectious Disease, Institute of Liver and Biliary Sciences, New Delhi, India.
  • Govind Mawari Centre for Occupational and Environment Health (COEH), Maulana Azad Medical College, New Delhi, India.
  • Udbhav Sharma Department of Medicine, Maulana Azad Medical College, New Delhi, India.
  • Maryam Hussain Department of Medicine, Maulana Azad Medical College, New Delhi, India.
  • CP Baveja Department of Microbiology, Maulana Azad Medical College, New Delhi, India.
Keywords: Healthcare Associated Infections (HAI), Ventilator Associated Pneumonia (VAP), Catheter Associated Urinary Tract Infection (CAUTI), Central Line Associated Bloodstream Infection (CLABSI)

Abstract

Background: Global prevalence of healthcare associated infections (HAI) ranges anywhere between 7% and 12% as per WHO estimates. This study was undertaken to understand the pattern and types of HAI at a selected healthcare facility and determine the common causative agents and their antibiotic susceptibility profile.

Methods: One hundred consecutive patients diagnosed with HAI were enrolled and monitored; the causative organisms isolated on culture were recorded and their sensitivity profile was generated.

Results: There were a total of 110 hospital acquired infections with 10 patients having two infections each. 69 patients had ventilator associated pneumonia (VAP), 21 catheter associated urinary tract infection (CAUTI) patients, 20 central line associated bloodstream infection (CLABSI), and 10 patients had both VAP and CAUTI. All of the HAIs were device associated. 76 pathogens were isolated on culture. No organism was isolated in 40 HAI. Majority (94.7%) of the organisms were gram-negative and all were multidrug resistant. Seventy-seven of the enrolled patients expired while 23 were discharged from the hospital

Conclusions: This study demonstrated that HAIs occur in patients of all age groups; younger patients are not spared. Majority of the HAIs were caused by multidrug resistant gram-negative bacteria and were associated with high patient mortality. Acinetobacter species was the most common organism associated with HAI.

How to cite this article:
Wasi S, Daga MK, Mawari G, Kumar N, Sharma U, Hussain M, Baveja CP. Current Pattern and Clinico-Bacteriological Profile of Healthcare Associated Infections in an ICU Setting: A Study from a Tertiary Care Centre in Delhi. J Adv Res Med. 2022;9(1):1-10.

DOI: https://doi.org/10.24321/2349.7181.202201

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Published
2022-02-14

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