Henoch-Schönlein Purpura in Young Adult Male - Is Vitamin C the Culprit?

  • Saurabh Gupta MBBS Student, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Keywords: Ascorbic Acid (Vitamin C), Henoch-Schönlein Purpura, Maculopapular Rashes, Polyarthralgia, Subconjunctival Haemorrhage

Abstract

A 21 year old male patient presented with bilateral lower and upper limb rashes, polyarthralgia, hematemesis, per rectal bleeding, abdominal pain, suggesting systemic vasculitis. He developed bilateral subconjunctival haemorrhage. His Vitamin C analysis was done using ELISA method and it revealed significantly low level of Vitamin C. Tissue biopsy was consistent with IgA vasculitis/Henoch-Schönlein purpura. Also, the cause of Henoch-Schönlein Purpura is unknown.

How to cite this article:
Gupta S. Henoch-Schönlein Purpura in Young Adult Male - Is Vitamin C the Culprit?. J Adv Res Med 2019; 6(4): 13-15.

DOI: https://doi.org/10.24321/2349.7181.201919

References

May JM, Harrison FE. Role of vitamin C in the function of the vascular endothelium. Antioxid Redox Signal. 2013; 19(17): 2068–2083. doi:10.1089/ars.2013.5205. https://www.liebertpub.com/doi/10.1089/ars.2013.5205

Vairo G1, Salustri A, Trambaiolo P, D’Amore F. Scurvy mimicking systemic vasculitis Minerva Med. 2002

Apr;93(2):145-50.

Friesgaard Christensen, A., Clemmensen, O., & Junker, P. (2013). Palpable purpura with an unexpected

outcome. Case reports in rheumatology, 2013, 678427. https://doi.org/10.1155/2013/678427.

Horton JC. Disorders of the Eye. In: Jameson, Fausi, Kasper, Hauser, Longo, Loscalzo (Eds). Harrison’s

Principles Of internal Medicine. 20th ed. McGraw-Hill; 2018. p181.

Akbulut Y, Büyüktortop N, Şanlı C, Yumuşak E, Oğurel T. Subconjunctival hemorrhage in Henoch-

Schonlein purpura: a case report and literature review. Ortadogu Tıp Derg 2019; 11(3): 349-352. https://doi.

org/10.21601/ortadogutipdergisi.453297.

Harper L, Nuttall SL, Martin U, Savage CO. Adjuvant treatment of patients with antineutrophil cytoplasmic

antibodyâ€associated vasculitis with vitamins E and C reduces superoxide production by neutrophils.

Rheumatology 2002; 41(3): 274-278.

Published
2020-05-14