Agranulocytosis - A Rare Side Effect of Standard  Dose Ceftriaxone Therapy

Sachin Kumar; Satish Kumar; Priya Singh

Sachin Kumar Senior Resident, Department of Pulmonary and Critical Care Medicine, King Georgeâ€™s Medical University, Lucknow, Uttar Pradesh, India
Satish Kumar Assistant professor, Department of Medicine, king Georgeâ€™s Medical University, Lucknow, Uttar Pradesh, India
Priya Singh MD Pathology, Excel Diagnostics, Lucknow, Uttar Pradesh, India.

Keywords: Agranulocytosis, Ceftriaxone, Chemotherapeutic Agents, G-CSF

Abstract

In the current era of medical science, agranulocytosis is rarely found. Chemotherapeutic agents and various non-chemotherapeutic drugs commonly cause agranulocytosis. Agranulocytosis can occur any time
during the therapy in hospital, and patients may remain symptomless. So, we should do regular cell count to reach the diagnosis in such cases. An appropriate antibiotic or drug-change, investigations to rule out
sepsis and granulocyte colony-stimulating factor (G-CSF) injection can be given as the management part. The patient should be monitored daily and observed till the normalization of neutrophil counts. Here,
we report a case of ceftriaxone-mediated agranulocytosis, which was completely reversible after withdrawing the antibiotic.

How to cite this article:
Kumar S, Kumar S, Singh P. Agranulocytosis - A Rare Side Effect of Standard Dose Ceftriaxone Therapy. J Adv Res Med. 2022; 9(1): 24-26.

DOI: https://doi.org/10.24321/2349.7181.202205

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