The Effect of Alcoholic and Aqueous Extracts of Malva Sylvestris L. on the Vitality of Protoscolices in Echinococcus Granulosus (In Vitro and In Vivo)

Abdullah  Huseen Jasim

Abdullah Huseen Jasim Ministry of Education, Directorate of Ninevah Education, Mosul, Iraq.

Keywords: Hydatidosis, Echinococcus Granulosus, Protoscolices, Extracts of Malva Sylvestris L

Abstract

Introduction: Medicinal plants are an important source of compounds that contain effective biological substances for the treatment of serious diseases all over the world.
Aim: The study aimed to determine the effect of aqueous and alcoholic extracts of Malva sylvestris L. leaves on the vitality of protoscolices in vitro and in vivo.
Results: The results of this study showed that the alcoholic and aqueous extracts had an inhibitory effect on protoscolices compared with the control group in all concentrations. Their vitality was measured using dye
eosin, which is based on changing the green colour of living protoscolices to red after killing them. The results of this study showed that the concentration of 60 mg/ml for both alcoholic and aqueous extracts
showed the highest reduction in the vitality of the protoscolices, by killing them (100% at all exposure times (60, 40, 30, and 15 minutes) in case of alcoholic extract, while the percentage of reducing their vitality
with the aqueous extract was 100% at 60 and 40 minutes, and at 30 and 15 minutes, the percentages were 9.67% and 19.32% compared to the control group (94.84% and 96.98%, respectively)).
Conclusion: The alcoholic and aqueous extracts of M. sylvestris leaves were able to kill protoscolices in vitro. It was also seen that the alcoholic extract showed a greater effect than the aqueous extract.

How to cite this article:
Jasim AH. The Effect of Alcoholic and Aqueous Extracts of Malva Sylvestris L. on the Vitality of Protoscolices in Echinococcus Granulosus (In Vitro and In Vivo). J Commun Dis. 2023;55(3):40-47.

DOI: https://doi.org/10.24321/0019.5138.202336

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