Immune State Assessment in People with Diabetes Mellitus

Mohammad J. Al-Jassani; Ahmed  Adnan; Zainab  H J Alhassona; Thair  L Mizal; Hani  Moslem Ahmed; Wathiq  Kh Mohammed; Nidhal  Hassan Sayyid

Mohammad J. Al-Jassani Department of Forensic Science, College of Science, Al-Karkh University of Science, Iraq.
Ahmed Adnan Medical Lab. Techniques Department, College of Medical Techology, Al-Farahidi University, Iraq.
Zainab H J Alhassona College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq.
Thair L Mizal Medical Lab. Techniques Department, Al-Esraa University College, Baghdad, Iraq.
Hani Moslem Ahmed Department of Dental Industry Techniques, Al-Noor University College, Nineveh, Iraq.
Wathiq Kh Mohammed Medical Lab. Techniques Department, Al-Hadi University College Baghdad, Iraq.
Nidhal Hassan Sayyid College of nursing, National University of Science and Technology, Dhi Qar, Iraq.

Keywords: Diabetes, IL-6, IL-8, Immunity

Abstract

Introduction: Diabetes is a metabolic condition characterised by high blood sugar levels, which can be caused by insulin resistance or insufficient insulin production by the body, which leaves cells
unresponsive to the hormone. The goal of this study was to explore the immune status in Diabetes Mellitus (DM) patients by determining their IL-6 and IL-8 levels.
Method: Ninety diabetic patients, ranging in age from 30 to 65 years were selected for the study and 10 individuals were selected as control. All diabetic patients were admitted to the clinic in the province of
Baghdad. 5 ml of blood sample was drawn from each subject for serum separation. The participant’s information was written on the label of the tube, which was used for the IL-6 and IL-8 assays, which were
purchased from the MyBioSource Company, USA. These tests were done according to the company’s instructions.
Results: The current study showed an increase in the levels of IL-6 and IL-8 in patients with diabetes as compared to the control group.
Conclusion: The results of the study show that DM patients’ blood levels of IL-6 and IL-8 have increased along with their general health.
This indicates that immune response pathways may differ between individuals with and without diabetes.

How to cite this article:
Mohammed WKD, Adnan A, Alhassona ZHJ, Mizal TL, Ahmed HM, Sayyid NH, Jassani MJA. Immune State Assessment in People with Diabetes Mellitus. J Commun Dis. 2023;55(3):90-92.

DOI: https://doi.org/10.24321/0019.5138.202344

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