Association of IgG and IgM Levels of CMV Infection with Abortion among Women who Smoke

  • Hafidh l AI Adi College of MLT, Ahl Al Bayt University, Kerbala, Iraq.
  • Mohammed Haider Hamad Medical Laboratory Techniques Department, Al Mustaqbal University College, Babylon, Iraq.
  • Ali A Fadhil Medical Technical College, Al-Farahidi University, Iraq.
  • Shaymaa Abdul Hameed Khudair Advanced Biomedical Science, Al Nisour University College, Baghdad, Iraq.
  • Anwar Sabbah Hussen Al-Hadi University College, Baghdad, Iraq.
  • Ahmed S Abed Department of Prosthetic Dental Technology, Hilla University College, Babylon, Iraq.
  • Thabit Moath Omar Department of Medical Laboratory Technics, Al Noor University College, Bartella, Iraq.
Keywords: Association, CMV Infection, Abortion, Smoking, Women

Abstract

Introduction: Human Cytomegalovirus (CMV) infection has become common worldwide. The current study was suggested to evaluate the impact of smoking on abortion in Human Cytomegalovirus (CMV) infected women.
Method: The study was conducted on 66 women IgG and IgM were used to detect CMV infection in women who had undergone abortion.
Results: The current results showed significant differences in the number of births and marriage duration (p=0.009, p=0.010) and non-significant difference in age (p=0.750) in both groups. There was a high percentage of smokers (21.21%) in women with abortion as compared to the healthy group. There were significant elevations of IgG (2.32 ± 0.53) and IgM (0.51 ± 0.312) levels in women who had undergone abortion (p = 0.000) as compared to healthy women. A significant inverse association between IgG level and number of abortions (p=0.019), and a non-significant weak correlation between IgM and number of abortions (p=0.969) was noted. The impact of smoking on the number of abortions and birth showed non-significant differences (p=0.871, p=0.955) respectively between smoker and non-smoker groups. Healthy women didn’t have any abortion and showed non-significant differences in the number of births (p=0.430) in comparison with abortion group. The effect of smoking on the levels of IgG and IgM of study groups shows non-significant changes.
Conclusion: The current study concluded that smoking does not contribute to abortion in any direct effect, but it may lead to CMV infection by weakening the immune response.

How to cite this article:
Hafidh l AI Adi, Hamad MH, Fadhil AA, Khudair SAH, Hussen AS, Abed AS, Omar TM. Association of IgG and IgM Levels of CMV Infection with Abortion among Women who Smoke. J Commun Dis. 2022;54(4):15-20.

DOI: https://doi.org/10.24321/0019.5138.202297

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Published
2022-12-31

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