Clinico-aetiological Profile of Severe Anaemia in Hospitalised Adolescents in a Tertiary Care Centre of Bundelkhand Region, Central India

  • Aradhana Kankane Associate Professor, Department of Paediatrics, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India
  • Anshu Gautam Junior Resident, Department of Paediatrics, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India.
  • Nupur Pandey Assistant Professor, Department of Paediatrics, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India
  • Om Shankar Chaurasia Professor & Head, Department of Paediatrics, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India.
Keywords: Adolescent, Severe Anaemia, Clinical Profile, Aetiology, Bundelkhand Region

Abstract

Background: Anaemia is a worldwide public health issue and developing countries are burdened with it because of malnutrition, iron deficiency, vit. B12 deficiency, folic acid deficiency, and infectious diseases. It affects 1.6 billion people (24.8%) globally.

Objective: To study the clinico-aetiological profile of severe anaemia in adolescent patients admitted to the paediatrics department of a tertiary care centre in the Bundelkhand region of Central India.

Methods: The study design of the present study was cross-sectional observational. The study included 100 cases of severe anaemia aged 10-19 years fulfilling the inclusion and exclusion criteria. It was conducted
from September 2021 to August 2022. Adolescents with haemoglobin levels less than 8 gm/dl are considered severely anaemic according to WHO. SPSS version 23 was used to perform statistical analysis.

Result:Out of 100, most of the patients were from rural areas (55%). The commonest affected age group was the early adolescent (10-12 years) group with a female preponderance (67%) over male. Pallor (100%) was
the most common physical finding, the second most common being icterus followed by pedal oedema. Results of the present study showed that nutritional anaemia was the most common aetiology, out of which
iron deficiency anaemia (IDA) was found in 36% of cases followed by vit. B12 deficiency anaemia (24%) and iron + vit. B12 deficiency anaemia (8%). Predominant RBC morphology observed on peripheral blood smear was microcytic hypochromic (50%).

Conclusion: The study shows that nutritional deficiencies, i.e. iron and vit. B12, constitute the commonest cause of severe anaemia in hospitalised adolescents.

How to cite this article:
Kankane A, Gautam A, Pandey N, Chaurasia OS. Clinico-aetiological Profile of Severe Anaemia in Hospitalised Adolescents in a Tertiary Care Centre of Bundelkhand Region, Central India. Ind J Youth Adol Health. 2023;10(1):16-20.

DOI: https://doi.org/10.24321/2349.2880.202304

References

Dasharatham P, Reddy VS. A study of etiological and clinical profile of patients with severe anemia in a

tertiary care hospital. Int J Adv Med. 2018;5:1422.

World Health Organization [Internet]. Haemoglobin concentrations for the diagnosis of anaemia and

assessment of severity. Vitamin and Mineral Nutrition Information System; 2011 [cited 2022 Oct 3].

Available from: https://apps.who.int/iris/bitstream/handle/10665/85839/WHO_NMH_NHD_MNM_11.1_

eng.pdf [Google Scholar]

Technical handbook on anaemia in adolescents. Weekly iron and folic acid supplementation programme. 1 p.

[cited 2017-18].

Sinha AK, Karki GM, Karna KK. Prevalence of anemia amongst adolescents in Biratnagar, Morang Dist. Nepal.

Int J Pharm Biol Arch. 2012;3(5):1077-81. [Google Scholar]

Kar SK, Choudhury A, Singh AP. Understanding normal development of adolescent sexuality: a bumpy ride.

J Hum Reprod Sci. 2015 Apr-Jun;8(2):70-4. [PubMed] [Google Scholar]

United Nations International Children’s Emergency Fund [Internet]. Adolescent development and participation;

[cited 2022 Dec 24]. Available from: https://www.unicef.org/india/what-we-do/adolescent-developmentparticipation

Ministry of Health and Family Welfare, Government of India [Internet]. National Family Health Survey (NFHS5) 2019-21. Compendium of fact sheets; [cited 2022 Dec 24]. Available from: https://main.mohfw.gov.in/

sites/default/files/NFHS-5_Phase-II_0.pdf

Chauhan S, Kumar P, Marbaniang SP, Srivastava S, Patel R. Prevalence and predictors of anaemia among

adolescents in Bihar and Uttar Pradesh, India. Sci Rep. 2022;12(1):8197-205. [PubMed] [Google Scholar]

Shinde M, Shinde A, Shrivastava A. Prevalence of anemia among adolescent girls in urban area of Central

Madhya Pradesh.J Evol Med Dent Sci. 2015;4(56):9750-4. [Google Scholar]

Sood P, Bindra S. Modified Kuppuswamy socioeconomic scale: 2022 update of India. Int J Community Med

Public Health. 2022;9:3841.

Kumar A, Gupta S, Meena LP, Meher MP, Rai M, Kumar S, Bharti A. Study to evaluate the etiology of iron

deficiency anemia at a teaching hospital in northeastern part of India. J Family Med Prim Care. 2020;9(6):3076.

[PubMed] [Google Scholar]

Reddy DM, Kalyani A, Shalini A. A study of clinicopathological patterns of anemia in different

groups of schoolchildren. Int J Sci Stud. 2021;8(12):186-91. [Google Scholar]

Venkatesh G, Talawar S, Shah BH. Clinical profile of anemia in children. IOSR J Dent Med Sci. 2013;10(5):65-

Ramya P, Premalatha P, Tejeswini V, Chitturi R, Renuka IV. Hematological profile of anemias in children in a tertiary hospital. Indian J Pathol Res Pract. 2018;7(11):1159-66. [Google Scholar]

Madoori S, Ramya C, Valugula S, Sandeep G, Kotla S. Clinico hematological profile and outcome of anemia

in children at tertiary care hospital, Karimnagar, Telangana, India. Int J Res Med Sci. 2015;3(12):3567-71.

Sastry CP. Study on clinical and hematological profile of anemia in children aged 5 to 12 years in rural Telangana. J Pediatr Res. 2017;4(7):488-93.

Prakash A, Kumar A, Awasthi S, Dutta S, Mittal A. Clinicopathological pattern of anemia in children in

age group upto 18 years. Int J Med Res Prof. 2018 Jan;4(1):262-5.

Khunger JM, Arulselvi S, Sharma U, Ranga S, Talib VH. Pancytopenia - a clinico haematological study of 200

cases. Indian J Pathol Microbiol. 2002 Jul;45(3):375-9. [PubMed] [Google Scholar]

Gayathri BN, Rao KS. Pancytopenia: a clinico hematological study. J Lab Physicians. 2011;3(1):15.

[PubMed] [Google Scholar]

Published
2023-03-31