Can Rabies Vaccine-Induced Antibodies or Intravenous Rabies Immunoglobulins Help Neutralise Snake Venoms for Early Mitigation of Snakebite-Related Toxicity?: An Exploratory Protocol
Abstract
Many scientists are looking for ways to achieve early mitigation of snakebite toxicity to minimise death and disability caused by snake envenomation. The rabies virus glycoprotein, with homologies to snake venom/ toxins, can alter behaviour in animals through the inhibition
of nicotinic acetylcholine receptors (nAChRs) present in the central nervous system. Based on this principle of homology between rabies
G protein similar to snake venom toxin, there should be an experiment to analyse whether rabies anti bodies (primarily against the G protein
of the rabies virus) can neutralise snake venom peptides like that of alpha-bungarotoxin etc. and help mitigate snake venom-induced toxicity at the earliest.
How to cite this article:
Bharti O K. Can Rabies Vaccine-Induced Anti bodies or Intravenous Rabies Immunoglobulins Help Neutralise Snake Venoms for Early Mitigation of Snakebite-Related Toxicity?: An Exploratory Protocol. Epidem Int. 2023;8(4):1-3.
DOI: https://doi.org/10.24321/2455.7048.202312
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