Antibacterial Activity of Homoeopathic Medicine Hepar Sulphuricum 200 C & 1 M against Lung Pathogens - In Vitro

  • Sivaramyapragathi R S Senior Research Fellow, National Homoeopathy Research Institute in Mental Health (NHRIMH), Kottayam, Kerala, under CCRH, Ministry of AYUSH, Government of India
  • Sisir P R Professor & Head, Department of Paediatrics, Sarada Krishna Homoeopathic Medical College, Kulasekharam, Kanyakumari
  • Muthulakshmi Akshaya M Research Scholar, Department of Paediatrics, Sarada Krishna Homoeopathic Medical College, Kulasekharam, Kanyakumari
Keywords: Hepar sulphuricum, homoeopathy, antibacterial activity, Staphylococcus aureus, Klebsiella pneumoniae, zone of inhibition, short communication

Abstract

Introduction: Antibiotic resistance is one of the most significant global health problems. It occurs when bacteria adapt to the use of antibiotics, leading to resistance. Certain bacterial strains have developed resistance to nearly all available medications, necessitating the discovery of new antibacterial drugs.
Objective: To evaluate the antibacterial activity of homoeopathic medicines using zone of inhibition (ZOI) analysis against specific bacterial strains
Methods: The study involved the preparation of broth cultures of the targeted organisms, allowing colonies to form. The ZOI and minimum inhibitory concentration were assessed for each sample against
Staphylococcus aureus and Klebsiella pneumoniae. Hepar sulphuricum 200 C and 1 M were tested for their antibacterial activity. Dispensing alcohol was used as a vehicle control.
Results: Hepar sulphuricum 200 C and 1 M exhibited significant antibacterial activity against both Staphylococcus aureus and Klebsiella pneumoniae. The ZOI was measured, confirming the antibacterial effect
of the homoeopathic medicine.
Conclusion: The study demonstrated that the homoeopathic medicine Hepar sulphuricum 200 C and 1 M has an effective antibacterial effect against Staphylococcus aureus and Klebsiella pneumoniae, providing a potential alternative in combating resistant bacterial strains.

How to cite this article:
Sivaramyapragathi R S, Akshaya M M, Sisir P R.
Antibacterial Activity of Homoeopathic Medicine
Hepar Sulphuricum 200 C & 1 M against Lung
Pathogens - In Vitro. Chettinad Health City Med
J. 2025;14(3):45-50.

DOI: https://doi.org/10.24321/2278.2044.202539

References

Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases,

Division of Healthcare Quality Promotion. Antibiotic resistance and infection prevention guidance [Internet].

Atlanta (GA): CDC; [cited 2025 Oct 14]. Available from:https://www.cdc.gov/ncezid/dhqp/

Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. P T. 2015 Apr;40(4):277-83. [PubMed] [Google Scholar]

Levy SB, Marshall B. Antibacterial resistance worldwide: causes, challenges and responses. Nat Med. 2004;10(12 Suppl):S122-9. [PubMed] [Google Scholar]

Published
2025-10-18