Neurological Challenges in Burkitt Lymphoma: A Case Report of Vincristine-Induced Neuropathy

Yash Radhanpura; Harshil Gadhiya; Saurabh Sanja; Riddhi Shingala; Dhirangi Gajipara

Yash Radhanpura Student, School of Pharmacy, R K University, Rajkot, Gujarat, India
Harshil Gadhiya Student, School of Pharmacy, R K University, Rajkot, Gujarat, India
Saurabh Sanja Student, School of Pharmacy, R K University, Rajkot, Gujarat, India
Riddhi Shingala Student, School of Pharmacy, R K University, Rajkot, Gujarat, India
Dhirangi Gajipara Student, School of Pharmacy, R K University, Rajkot, Gujarat, India

Keywords: Burkitt Lymphoma (BL), Non-Hodgkin Lymphoma (NHL), Motor Axonal Polyneuropathy, Vincristine (VCR), Peripheral Nervous System (PNS)

Abstract

Non-Hodgkin lymphoma-related immune-mediated neuropathies are uncommon and might be challenging to distinguish from neuropathies caused by other aetiologies. We present the medical and pathological data of a 16-year-old patient who had Burkitt-like cancer. Motor axonal polyneuropathy was suspected due to the neuropathy characteristics, which developed during chemotherapy induction with a cumulative dosage of 0.4 mg vincristine. Our theory is that the lymphoma-induced immunological mechanisms caused disruption to the peripheral nervous system (PNS), making it more susceptible to vincristine’s harmful effects.

How to cite this article:
Radhanpura Y, Gadhiya H, Sanja S, Shingala R,
Gajipara D. Neurological Challenges in Burkitt
Lymphoma: A Case Report of Vincristine-Induced
Neuropathy. Chettinad Health City Med J.
2025;14(3):42-44.

DOI: https://doi.org/10.24321/2278.2044.202538

Author Biography

Dhirangi Gajipara, Student, School of Pharmacy, R K University, Rajkot, Gujarat, India

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