A Study on the Impact of Endoscopic Myomectomy on Reproductive Outcomes of Assisted Reproductive Technology
Abstract
Introduction: Uterine fibroids (myomas or leiomyomas) are the most common benign tumours in women of reproductive age. They have varied clinical presentations ranging from being asymptomatic to being a major source of clinical morbidity. The presence of uterine fibroids has been linked to fertility problems.
Aims: The primary objective of the study is to evaluate the effect of endoscopic myomectomy on IVF outcomes in patients with fibroids in terms of pregnancy rate, implantation rate, and ongoing pregnancy rate. Miscarriage rates and ectopic and heterotopic pregnancy rates were also studied as secondary objectives.
Method: This single-centre, retrospective observational study was conducted on patients with uterine myoma who visited Chennai Fertility Centre and Research Institute, Chennai for infertility treatment during
the period of June 2013 to June 2022.
Statistical analysis used: The collected data was presented as a mean and standard deviation, frequency, or percentage. Pearson’s chisquare test was used to assess the association between IVF outcome and variables. Tests that were statistically significant at < 0.05 were considered. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) software version 24.0.
Results: The results showed higher ongoing pregnancy rates in the study group compared to the control group (68.89% vs. 42.2%) with a statistically significant difference in the p value (0.011).
Conclusion: It can be concluded that endoscopic myomectomy, either laparoscopic or hysteroscopic, can be used as a treatment for submucosal and large (> 4 cm) intramural fibroids and can improve the clinical pregnancy rate and cumulative implantation rate of infertile patients with fibroids.
How to cite this article:
Nandi L, Sridev S, Thomas V M, Kulshrestha S,
Lakshmanan K, Abinaya R. A Study on the Impact
of Endoscopic Myomectomy on Reproductive
Outcomes of Assisted Reproductive Technology.
Chettinad Health City Med J. 2024;13(3):18-22.
DOI: https://doi.org/10.24321/2278.2044.202439
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