A Rare Case Report: Diagnostic Challenge of Uncommon Site of Lymphoma Camouflaging as Cellulitis

  • KV Prarthana 3rd-year Postgraduate, Department of General Surgery, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, Tamil Nadu, India.
  • Anantharamakrishnan Professor, Department of General Surgery, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, Tamil Nadu, India.
  • Amrithraj T Associate Professor, Department of General Surgery, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, Tamil Nadu, India.
Keywords: Primary Skeletal Lymphoma, Extranodal, Diffuse Large B Cell Lymphoma

Abstract

Lymphomas are solid tumours of the immune system accounting for 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHL) are a heterogeneous group of lymphoproliferative disorders originating in B cells, T cells or natural killer T-cells. They have a vast array of clinical presentations and histological findings which can make diagnosis difficult. Lymph nodes, spleen, and liver are common sites of NHL. Extranodal soft tissue manifestation of NHL is a rare presentation of all lymphomas with a common occurrence in the geriatric population. Prevalent NHL is diffuse large B cell lymphoma which has significant clinical, morphological, and molecular heterogeneity leading to difficulty in timely diagnosis and treatment, and usually denotes an advanced stage. Here we throw light on primary skeletal muscle lymphoma-diffuse large B cell type, in an 81-year-old female patient mimicking cellulitis. It is vital to differentiate lymphoma from other entities to avoid perplexity in management.

How to cite this article:
Prarthana KV, Anantharamakrishnan, Amrithraj T. A Rare Case Report: Diagnostic Challenge of Uncommon Site of Lymphoma Camouflaging as Cellulitis. Chettinad Health City Med J. 2023;12(1):104-106.

DOI: https://doi.org/10.24321/2278.2044.202317

References

Lim CY, Ong KO. Imaging of musculoskeletal lymphoma. Cancer Imaging. 2013;13(4):448-57. [PubMed] [Google Scholar]

Surov A. Imaging findings of skeletal muscle lymphoma. Clin Imaging. 2014;38(5):594-8. [PubMed] [Google Scholar]

Alamdari A, Naderi N, Peiman S, Shahi F. Non-Hodgkin lymphoma with primary involvement of skeletal muscle. Int J Hematol Oncol Stem Cell Res. 2014;8:55-7. [PubMed] [Google Scholar]

Komatsuda M, Nagao T, Arimori S. [An autopsy case of malignant lymphoma associated with remarkable infiltration in skeletal muscles (author’s transl)]. Rinsho Ketsueki. 1981 Jun;22(6):891-5. Japanese. [PubMed] [Google Scholar]

Samuel LM, White J, Lessells AM, Roddie H, Matheson LM. Primary non-Hodgkins lymphoma of muscle. Clin Oncol (R Coll Radiol). 1999;11(1):49-51. [PubMed] [Google Scholar]

Beggs I. Primary muscle lymphoma. Clin Radiol. 1997 Mar;52(3):203-12. [PubMed] [Google Scholar]

Kandel RA, Bédard YC, Pritzker KP, Luk SC. Lymphoma. Presenting as an intramuscular small cell malignant tumor. Cancer. 1984 Apr 1;53(7):1586-9. [PubMed] [Google Scholar]

Bertoni F, Sanna P, Zucca E, Roggero E, Cavalli F. Primary extranodal lymphoma of skeletal muscles: a report of four cases. Oncol Rep. 1998 May-Jun;5(3):605-7. [PubMed] [Google Scholar]

Published
2023-03-31